Bioindicators in radiation protection

Abstract

Biodosimetry is the evaluation of absorbed dose using bioindicators. Among chromosomal aberrations, scoring of dicentrics from peripheral human blood has been used as gold standard for biodosimetry, although in case of large scale incidents its use presents some drawbacks. Advances in technology have led to new investigations allowing or permitting the use of new methods which not only improve this "classical" biodosimetry but permits the design of other bioindicators making possible faster analyses, particularly in events where many persons may have been exposed. This report presents an overview of some recent studies developed by the "Grupo de Estudos em Radioproteção e Radioecologia -GERAR", Nuclear Energy Department of UFPE -Brazil, involving biodosimetry.

Proteção Radiológica em Radiologia Médica

“…há relato de um caso em Recife, no ano de 2008, em que um médico intervencionista apresentou radiodermatite avançada nas mãos demonstrado pela figura 2, mas que o mesmo associou a lesão como reação alérgica ao látex da luva cirúrgica. [31].…”

Non-linear dynamics of chromosome condensation induced by colcemid

“…Some researchers have added colcemid, the synthetic analog of colchicine, earlier in order to prevent all the cells progressing into a second cell cycle (Sasaki et al 1989;Hayata et al 1992;Kanda et al 1994;Fernandes et al 2008). This is a very important method when the purpose is to score the chromosome aberrations in irradiated lymphocytes from the human peripheral blood Amaral et al 2008). On the other hand, one of the drawbacks with this method is that it induces highly condensed chromosomes (Kanda et al 1994;Fernandes et al 2008).…”