Quantification of iodine in porous hydroxyapatite matrices for application as radioactive sources in brachytherapy

Abstract

In this study, non-radioactive iodine was incorporated in two types of biodegradable hydroxyapatite-based porous matrices (HA and HACL) through impregnation process from sodium iodine aqueous solutions with varying concentrations (0.5 and 1.0 mol/L) . The results revealed that both systems presented a high capacity of incorporating iodine into their matrices. The quantity of incorporated iodine was measured through Neutron Activation Analysis (NAA). The porous ceramic matrices based on hydroxyapatite demonstrated a great potential for uses in low dose rate (LDR) brachytherapy.

All-Solid-State Iodide Selective Electrode for Iodimetry of Iodized Salts and Vitamin C

“…The most familiar iodine deficiency disorder (IDD) arising from low iodine diets is goiter. The other consequences of IDD are elaborated in other reports 2 .…”

Biocompatibility, osteointegration, osteoconduction, and biodegradation of a hydroxyapatite-polyhydroxybutyrate composite

“…Ceramics like hydroxyapatite (HA) have been used as bone substitutes, especially in human dentistry, as they are biocompatible, bioactive and osteoconductive, leading to bone regeneration in short periods of time (Borges et al, 2000;Fujibayashi et al, 2003;de Godoy et al, 2005;Lacerda et al, 2007;Sá et al, 2007). Direct contact with bone formed within its porous structure and biodegradation allowed bone tissue to develop and replace HA (Macneill et al, 1999;Borges et al, 2000;Rumpel et al, 2006).…”