2007
DOI: 10.1590/s1516-84842007000300018
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Alterações oculares nas doenças falciformes

Abstract: IntroduçãoO desenvolvimento nas práticas do cuidado associado à utilização racional dos hospitais-dia, bem como aos avanços das ciências básicas e pesquisas clínicas na doença falciforme (DF), trouxeram aumento expressivo da sobrevida dos portadores da DF, nos últimos trinta anos.A DF se caracteriza pela presença da hemoglobina S, responsável pelo fenômeno da falcização, através da polimerização desta hemoglobina. 1 A fisiopatologia da falcização envolve, além da presença de hemoglobina S, fatores adicionais, … Show more

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Cited by 5 publications
(9 citation statements)
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“…5,7,12 Retinal changes characterize sickle cell retinopathy, which may be non-proliferative or proliferative and is divided into five stages. 1,10,12,13 Among the forms of sickle cell anemia, SS patients present a more severe systemic clinical picture than those with type SC. On the other hand, occlusive ocular effects are more predominant in SC patients, who present only moderate anemia and higher blood viscosity.…”
Section: Ocular Manifestationsmentioning
confidence: 99%
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“…5,7,12 Retinal changes characterize sickle cell retinopathy, which may be non-proliferative or proliferative and is divided into five stages. 1,10,12,13 Among the forms of sickle cell anemia, SS patients present a more severe systemic clinical picture than those with type SC. On the other hand, occlusive ocular effects are more predominant in SC patients, who present only moderate anemia and higher blood viscosity.…”
Section: Ocular Manifestationsmentioning
confidence: 99%
“…14 Individuals with SCD as well as sickle cell trait (AS) are at increased risk of developing increased intraocular pressure when they present with hyphema (bleeding in the anterior chamber of the eye). 12 Low fetal hemoglobin (HbF) is generally associated with increased intravascular sickling and is responsible for several vaso-occlusive complications in homozygous SS. 15 In addition, Roy et al associated proliferative retinopathy with low levels of HbF.…”
Section: Ocular Manifestationsmentioning
confidence: 99%
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