Immunomodulatory and growth-promoting effect of a probiotic supplemented in the feed of broiler chicks vaccinated against infectious bursal disease

Abstract

This study was designed to investigate the effects of a probiotic plus an immunomodulatory product on the growth performance, immune response and net economic returns of broiler chicks vaccinated against Infectious bursal diseases virus (IBDV). A flock of 350 day-old chicks were equally and randomly distributed in seven groups, each comprising 50 birds. A mixture of microorganisms (¹Probiotic) or Cyclophosphamide (immune suppressor) was offered through feed supplementation to different groups. The Probiotic, consisting of Lactobacillus species, Bifidobacterium, Streptococcus salivarius and Enterococcus faecium, in addition to Aspergillus oryza and Candida pintolopessii. Compared with control treatment group, the probiotic-supplemented chicks had better feed conversion ratio (FCR) (1.938 and 1.959), with significantly heavier live body weight 2141.0±34.2 and 2120.3±33.2, respectively. Similarly, their antibody titers against IBDV were significantly higher (941 and 832) on day 35. No morbidity and mortality were observed in these groups. This study suggests that a product composed of a probiotic and cyclophosphamide enhanced the growth rate as well as the immunity against infectious bursal disease virus of broilers chicks

The effects of dietary supplementation with different levels of Microzist as newly developed probiotics on growth performance, carcass characteristics, and immunological organs of broiler chicks

“…In like manner, weights of liver and bile were observed to be unaffected due to supplementation. The findings of the current study showed complete agreement with the observations of Awad et al (2009), Ahmadi (2011), and Naseem et al (2012 who did not report any significant differences on the influences of probiotic supplementation on lymphoid organs.…”

<b>Effect of dietary probiotic supplementation on carcass traits and haematological responses of broiler chickens fed shea butter cake based diets

“…Besides, Willis, Isikhuemhen, and Ibrahim (2007) also suggested that the bursa was the primary lymphoid organ in broilers and concluded that probiotics could increase the relative weight of bursa to body weight. In contrast, previous authors have reported a non-significant effect of probiotic supplementation on the relative organ weights including liver and bursa of Fabricious, as a proportion of body weight (Naseem, Rahman, Shafee, Sheikh, & Khan, 2012;Nawaz et al, 2016). The observed inconsistency might be attributed to the strains of probiotic, technique of preparation, administration dosage, diet composition and hygienic status (Zhang, Zhou, Ao, & Kim, 2012).…”

Probiotic level effects on growth performance, carcass traits, blood parameters, cecal microbiota, and immune response of broilers

“…The P4 treatment showed the highest (P<0.05) antibody response to Newcastle disease at 27 days of age and IgM response to SRBC at 36 days of age. ElBaky (2013), Naseem et al (2012) and Zakeri and Kashefi (2011) found higher antibody titers against influenza disease, infectious bursal disease and Newcastle disease virus, respectively, in broilers fed Protexin supplemented diets compared with the controls. Moreover, Rhee et al (2004) and Haghighi et al (2005) reported higher blood IgM against SRBC when probiotics were included in a broiler diet.…”