Saccharomyces Cerevisiae cell wall dietary supplementation on the performance and intestinal mucosa development and integrity of broiler chickens vaccinated against coccidiosis

Abstract

This study was carried out to verify if Saccharomyces cerevisiae cell wall (SCCW) dietary supplementation (0.2%) was capable of protecting the intestinal mucosa of broiler chickens vaccinated against coccidiosis. Body weight gain, feed intake, feed conversion and intestinal mucosa morphometric parameters and epithelial loss were evaluated. In the experiment,400 day-old male chicks were distributed according to a completely randomized design in a 2x2 factorial arrangement. The following treatments were applied: T1 - no vaccination/ no SCCW supplementation; T2 - no vaccination/SCCW supplementation; T3 - vaccination/no SCCW supplementation; and T4 - vaccination/SCCW supplementation to four replicates of 25 birds each. Birds were vaccinated on the first day of age using a spray vaccine (Coccivac B®, Coopers), containing E. acervulina, E. maxima, E. mivati and E. tenella. S. cerevisiae cell wall was supplied from the first day of age. Live performance, intestinal morphometric parameters and epithelial loss were evaluated at 14, 21 and 28 days of age. Performance was affected by vaccination only at 21-days of age, when body weight gain was reduced in the vaccinated birds, but no body weight difference was observed on day 28. Vaccine also increased the crypt depth (p<0.05) in the duodenum and jejunum, suggesting a high cell activity in the crypt:villus transition area to maintain the epithelial cell turnover. Villi number/area (103,269 µm²) was not affected (p>0.05) by vaccine or cell wall supplementation, and epithelial loss was more pronounced in the duodenum and jejunum. In conclusion, the findings of this study suggest that S. cerevisiae cell wall supplementation may be an useful management tool to maintain the intestinal integrity of broilers vaccinated against coccidiosis

Effect of dietary nucleotide supplementation on broiler intestinal histomorphology

“…In addition, Wu et al (2018) who mentioned that chickens fed the diets supplemented with 0.5% yeast nucleotides showed an increase in the height of the intestinal villi and the villus height to crypt depth ratio in the ileum. (2,5,8) or Nucleoforce ® (3, 6, 9) at7 th , th and 21 st day (H&E, X100).…”

“…The effect of different dietary of nucleotides supplementation (Nucleoforce ® and Immune force ® ) and control diets on intestinal villi length of broiler chicks was illustrated in table 7and figures (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15). During 1 st ,2 nd , 3 rd ,4 th and 5 th weeks of the experiment the result showed a significant (p ≤ 0.05) increase in intestinal villi length of nucleotides supplemented groups when compared with the control, although group B that fed Nucleoforce ® showed highest values among the three different groups.…”

“…Moreover, Pourabedin et al (2014) found that the addition of dietary yeast in diets of broilers significantly improves the villus height in the duodenum of the treated bird. Also, Luquetti et al (2012) who mentioned that S. cerevisiae yeast cell wall (YCW)supplementation in diets of broiler chickens may be a helpful management tool to keep out the integrity of intestinal epithelium of broiler chickens vaccinated against coccidiosis. They added that the intestinal villi of birds supplemented with YCW at rate of (2 g/kg) are higher than control, irrespective of a vaccination against coccidiosis.…”

Effects of glutamine on performance and intestinal mucosa morphometry of broiler chickens vaccinated against coccidiosis

“…Feed additives derived from yeast cell walls, such as mannanoligosaccharide and fructooligosaccharide show beneficial effects on reducing performance (Nollet et al, 2007) and epithelial cell losses (Luquetti et al, 2012) in vaccinated birds. Other additives such as herbal extracts (Allen, 2003), essential oil blends (Oviedo-Rondon et al, 2006) and probiotics (Stringfellow et al, 2011) also seem to protect the intestinal mucosa against mild coccidial infections generated by the vaccine.…”

Feed potentials of Saccharomyces cerevisiae biomass cultivated in palm oil and cassava mill effluents

“…Specifically, Saccharomyces cerevisiae has the tendency to confer immunity in ruminant animals. 61 Luquetti et al 76 reported that 0.2% supplementation of Saccharomyces cerevisiae in cell wall is capable of protecting the intestinal mucosa of broiler chickens vaccinated against coccidiosis.…”