Bioavailability of different methionine sources for growing broilers

Abstract

-The objective of this trial was to evaluate the bioavailability of DL-2-hydroxy-4-(methyl) butanoic acid (DL-HMBA) and a polyherbal ingredient (PHI) in relation to DL-methionine (DLM) on broilers. Nine hundred male broiler chickens of the Cobb 500 strain were fed from 22 to 42 days of age either a basal diet without industrial methionine supplementation or the basal diet supplemented with DL-HMBA at one of three levels (0.143, 0.286 and 0.429%) or DLM at one of three levels (0.093, 0.186 and 0.279%, each of which is 65% of the respective DL-HMBA level by weight) or PHI at one of the same three levels used for DLM (0.093, 0.186 and 0.279%). The weight gain, feed conversion ratio and relative weights of breast and abdominal fat were improved over that of basal diet-fed broilers by the addition of DL-HMBA and DLM to the diet. A simultaneous exponential regression analysis revealed that the relative bioavailability values for DL-HMBA and PHI were 52% and 5% of that of DLM, respectively, for weight gain, and 57% and 4%, respectively, for feed conversion ratio. Concerning breast meat yield, a simultaneous linear regression analysis (slope ratio) showed that the relative bioavailability for DL-HMBA was 65% of that of DLM. Considering all studied parameters together, the relative bioavailability values for DL-HMBA and PHI are 58% and 4.5% of that of DLM on a product basis.

Apparent ileal amino acid digestibility, gut morphometrics, and gene expression of peptide and amino acid transporters in broiler chickens fed low‐crude‐protein diets supplemented with crystalline amino acids with soybean meal, canola meal, or corn DDGS as protein feedstuffs

“…Met and Lys are the two limiting AA in plant-based poultry diets with potential roles, including protein synthesis, improving performance, antioxidant status, cellular metabolism, and immunological function. 15,16 The higher digestibility of Met and Lys in birds receiving NC diet in the current study could be partly explained by the drastic reduction in dietary CP (185 versus 140 kg −1 for grower diet) as a result of the drop in SBM inclusion from 265 to 75 kg −1 in PC and NC diets, respectively. This 72% reduction in dietary SBM level implied a reduction in intact protein and those three AA (Lys, Met, and Thr) in the low-CP diets.…”

Safety and efficacy of hydroxy analogue of methionine and its calcium salt (ADRY+®) for all animal species

“…Although some more recent papers (Zou et al., ; Agostini et al., ; Kluge et al., ; Vazquez‐Añon et al., ) appeared to demonstrate bioequivalence between HMTBa and dl ‐methionine in poultry, the FEEDAP Panel concludes on the weight of evidence that HMTBa is likely to be less efficacious than dl ‐methionine in all non‐ruminant species. The main reasons for this lower bioefficacy are (i) the fact that the gut microbiota of the small intestine compete with the host more for HMTBa than for dl ‐methionine (Drew et al., ; Malik et al., ), (ii) commercial HMTBa and its salts may contain besides the free acid/salt, significant amounts of dimers, trimers and oligomers, known to have a lower bioefficacy depending on the manufacturing process (Boebel and Baker, ; Saunderson, ; Van Weerden et al., ; Liu et al., ; Hoehler et al., ; Zimmerman et al., ; Dilger and Baker, ; Elwert et al., ; Shoveller et al., ; Opapeju et al., ; Zelenka et al., ; Sangali et al., ) (see Appendix A).…”

Продуктивність Та Забійні Якості Перепелів При Використанні Різних Джерел Метоніну В Раціонах

“…Тварині не потрібно витрачати додаткові життєві ресурси та енергії для переведення частини D-метіоніну в L-метіонін. Виходячи з отриманих в ході досліджень даних (Jiao et al, 2010;Kratzer, Littell, 2006;Kubińska et al, 2014;Liu et al, 2010;Mitchell, Lemme, 2008;Narayanswamy, Bhagwat, 2010;Paulicks et al, 2009;Sangali et al, 2014;Vazquez-Anon et al, 2006;Yi et al, 2007), очевидно, що джерела метіоніну мають різну ефективність. Тому метою наших досліджень було визначити вплив різних джерел метіоніну у комбікормах на продуктивність та забійні якості перепелів м'ясного напряму продуктивності.…”