Performance and intestinal health of broilers inoculated with nalidixic acid-resistant Salmonella Typhimurium and treated with organic acids

Abstract

-An experiment with 630 one-day-old chicks experimentally inoculated with Salmonella Typhimurium was performed to evaluate the effects of an organic acid blend (benzoic, fumaric and 2-hydroxi-4-methylltio-butanoicHMTBa) on intestinal health and performance. The experimental challenge with Salmonella Typhimurium occurred in two different routes of administration: via crop on the first day after hatching, and via feed, offered from seven to 14 days of age. These groups were treated with organic acids in a 3 × 2 (agent versus acid) factorial arrangement. Chicks treated with organic acids had higher weight gain, mean live weight and better feed conversion at 14 days of age, and higher weight gain at 28 days of age. Chicks treated with organic acids inoculated via crop had higher duodenum villi height than animals of the control group.Jejunum villi were higher in chicks of the negative control group compared with birds supplemented with organic acids. Small intestine pH in chicks of the inoculated group was lower compared with control group throughout the trial period. HMTBa acid in the dosage of 0.4% improves intestinal health and performance when nalidixic acid resistant Salmonella Typhimurium is experimentally inoculated.

Effect of dietary supplementation of lauric acid on growth performance, antioxidative capacity, intestinal development and gut microbiota on black sea bream (Acanthopagrus schlegelii)

“…In this study intestinal mucosal morphology height of villus and goblet cells number/villus height increased in LA supplemented diet from 0.0% to 0.1%. A similar result has been reported that organic acids in all diets may increase villus height [ 54 , 55 ].…”

“…In the current investigation intestinal mucosal morphology height of villus and goblet cells, number/villus height increased in LA supplemented diet from 0.0% to 0.1% suggesting that dietary supplements have played their role in increasing the height of villus in the intestine. In previous studies it was reported that organic acids are used as a food supplement, it can cause a significant increase in villus height [ 54 , 55 ]. In animals, the intestinal villus plays a vital role in food materials absorption and digestion as well as helps in boosting the immunity of an organism by providing a home to microbiota [ 56 ].…”

Phytate utilization using feed grade acidifiers to improve tibia composition, gut microbiology and intestinal pH of broiler chickens

“…It was also reported by Sheikh et al (2010) that organic acid supplementation increased villus height and other histological changes in the small intestines of broiler chickens. Similarly, Tatiane et al (2011) observed increased villus height in the small intestine of chickens that had access to acidified diets suggesting that reduction in intestinal contamination by non-desirable microorganisms supported development of villus morphometry. This according to the authors increased intestinal surface area and facilitated better nutrient absorption.…”