Potentially inappropriate medications among elderly Brazilian outpatients

Faustino, Christine; Passarelli, Maria Cristina Guerra; Jacob‐Filho, Wilson

doi:10.1590/s1516-31802013000100004

Cited by 33 publications

(42 citation statements)

References 42 publications

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“…Resultados semelhantes têm sido observados em investigações internacionais 30,31,32 e brasileiras 23,24,36 . Como já relatado em estudos anteriores, a polifarmácia tem sido associada a resultados negativos em saúde, como, por exemplo, reações adversas, interações medicamentosas, baixa adesão e síndromes geriátricas 9,37,38 . Corroborando esse quadro, a associação aqui observada evidencia um cenário de baixa qualidade da polifarmácia entre os idosos estudados, já que esta se constituiu em um fator de risco para o uso de medicamentos potencialmente inadequados.…”

Section: Métodosunclassified

Uso de medicamentos potencialmente inadequados entre idosos do Município de Viçosa, Minas Gerais, Brasil: um inquérito de base populacional

et al. 2015

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Resumo Avaliou-se o uso de medicamentos potencialmente inadequados entre idosos de Viçosa, Minas Gerais, Brasil, de acordo com os critérios de Beers 2012 e STOPP, bem como os fatores associados a esse uso. Estudo transversal com 621 idosos não institucionalizados, abordados por entrevista domiciliar. As variáveis explicativas foram sexo, idade, escolaridade, percepção da saúde, restrição de atividades nos últimos 15 dias, capacidade funcional, história de internação hospitalar, número de doenças autorreferidas e polifarmácia. Realizou-se análise de regressão de Poisson multivariada. Observou-se alta prevalência de uso de medicamentos potencialmente inadequados, 43,8% (IC95%: 37,8%-47,8%) e 44,8% (IC95%: 40,9%-48,8%), segundo os critérios de Beers 2012 e STOPP respectivamente. Sexo feminino e polifarmácia se mantiveram independentemente associados ao uso de medicamentos potencialmente inadequados, de acordo com os critérios de Beers. Para o critério STOPP, as variáveis independentemente associadas ao uso de medicamentos potencialmente inadequados foram sexo feminino, percepção de saúde regular e polifarmácia. Esforços são necessários para se qualificar a prática da polifarmácia entre idosos.

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Section: Métodosunclassified

Uso de medicamentos potencialmente inadequados entre idosos do Município de Viçosa, Minas Gerais, Brasil: um inquérito de base populacional

et al. 2015

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“…Other studies have found a relationship of female and increased risk for PIMs (Faustino, Passarelli, Jacob-Filho, 2013;Baldoni et al, 2014;Cassoni et al, 2014).…”

Section: Discussionmentioning

confidence: 86%

“…Studies conducted in health primary care centers, outpatient clinics and long term care settings have also reported a strong association between polypharmacy and risk of PIMs in Brazil (Oliveira et al, 2012;Faustino, Passarelli, Jacob-Filho, 2013;Santos et al, 2013;Vieira de Lima et al, 2013;Cassoni et al, 2014).…”

Section: Discussionmentioning

confidence: 99%

“…In Brazil, PIMs detection in primary care centers, hospital outpatients and institutionalized older adults have been evaluated mainly by 2003 Beers criteria (Obreli Neto, Cuman, 2011;Oliveira et al, 2012;Faustino, Passarelli, Jacob-Filho, 2013;Cassoni et al, 2014). STOPP criteria have been less used to evaluate PIMs in Brazilian subjects probably because it is designed for Europe and it is more recent than Beers criteria.…”

Section: Introductionmentioning

confidence: 99%

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Exposure to potentially inappropriate medications in Brazilian elderly outpatients with metabolic diseases

Martins

Mori

Dórea

et al. 2016

Braz. J. Pharm. Sci.

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“…Prevalence rates vary considerably across different studies involving inpatients: 5.3 -40.7% in the USA, 16.3 -52.6% in Canada, 19.8% in Europe, and 38.5% in Portugal (Curtis et al, 2004;Fialová et al, 2005;Maio, Del Canale, Abouzaid, 2010;Nyborg, Straand, Brekke, 2012;Oliveira Martins et al, 2006). In Brazil, prevalence rates range between 15.6% and 41% (Faustino, Passarelli, Jacob-Filho, 2013;Passarelli, Jacob-Filho, Figueras, 2005). However, it is important to take into account which version of the Beers Criteria was used in each analysis.…”

Section: Discussionmentioning

confidence: 99%

Does hospital admission provide an opportunity for improving pharmacotherapy among elderly inpatients?

Melo

Storpirtis

Ribeiro

2016

Braz. J. Pharm. Sci.

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The purpose of the work was to assess the incidence of potential drug interactions (pDDI), major pDDI, and the use of potentially inappropriate medication (PIM) at hospital admission, during hospitalization, and at discharge to evaluate whether hospital admission provides an opportunity for improving pharmacotherapy in elderly patients at a University hospital that has a clinical pharmacist. A prospective cohort study was carried out using data from the medical records of patients admitted to an internal medicine ward. All admissions and prescriptions were monitored between March and August 2006. Micromedex® DrugReax® and Beers Criteria 2015 were used to identify pDDI, major pDDI, and PIMs, respectively. A comparison of admission and discharge prescriptions showed the following: an increase in the proportion of patients using antithrombotic agents (76 versus 144; p<0.001), lipid modifying agents (58 versus 81; p=0.024), drugs for acid-related disorders (99 versus 152; p<0.001), and particularly omeprazole (61 versus 87; p=0.015); a decrease in the number of patients prescribed psycholeptics (73 versus 32; p<0.001) and diazepam (54 versus 13; p<0.001); and a decrease in the proportion of patients exposed to polypharmacy (16.1% versus 10.1%; p=0.025), at least one pDDI (44.5% versus 32.8%; p=0.002), major pDDI (19.9% versus 12.2%; p=0.010) or PIM (85.8% versus 51.9%; p<0.001). The conclusion is that admission to a hospital ward that has a clinical pharmacist was associated with a reduction in the number of patients exposed to polypharmacy, pDDI, major pDDI, and the use of PIMs among elderly inpatients.Uniterms:. Health Services/elderly patients. Internal Medicine/hospitals. Clinical Pharmacy. Drug interactions. Drug prescriptions.

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Potentially inappropriate medications among elderly Brazilian outpatients

Cited by 33 publications

References 42 publications

Uso de medicamentos potencialmente inadequados entre idosos do Município de Viçosa, Minas Gerais, Brasil: um inquérito de base populacional

Uso de medicamentos potencialmente inadequados entre idosos do Município de Viçosa, Minas Gerais, Brasil: um inquérito de base populacional

Exposure to potentially inappropriate medications in Brazilian elderly outpatients with metabolic diseases

Does hospital admission provide an opportunity for improving pharmacotherapy among elderly inpatients?

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