Si-TCP synthesized from "Mg-free" reagents employed as calcium phosphate cement

Motisuke, Mariana; Carrodeguas, Raúl García; Zavaglia, Cecília Amélia de Carvalho

doi:10.1590/s1516-14392012005000087

Cited by 8 publications

(2 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thus ions and silica released ions of 45S5 bioglass can absorb on the surface of the β-TCP grains and are incorporated into the crystalline structure, influencing its lattice parameters as well as atomic site occupancy (Qiu et al, 2013). This model supports the hypothesis that the addition of silica or silicon in the β-TCP provides a mechanism for the nucleation of a Si/α-TCP phase type at temperatures lower than those predicted by the conventional phase diagram (Reid et al, 2005;Pietak et al, 2007;Motisuke et al, 2012).…”

Section: 4supporting

confidence: 65%

Hierarchical structures of β-TCP/45S5 bioglass hybrid scaffolds prepared by gelcasting

Lopes

Magalhães

Gouveia

et al. 2016

Journal of the Mechanical Behavior of Biomedical Materials

Self Cite

View full text Add to dashboard Cite

This paper investigates the microstructure and the mechanical properties of β-tricalcium phosphate (β-TCP) three-dimensional (3D) porous materials reinforced with 45S5 bioactive glass (BG). β-TCP and β-TCP/x%-BG scaffolds with interconnected pores networks, suitable for bone regeneration, were fabricated by gel-casting method. Mechanical properties, porosity, and morphological characteristics were evaluated by compressive strength test, scanning electron microscopy (SEM) and X-ray microtomography analysis, whereas the structures were fully explored by XRD, and Raman spectroscopy. To the best of our knowledge, this is the first time where the mechanism for understanding the effect of bioglass on the mechanical properties and microstruture of β-TCP/45S5-BG scaffolds has been systematically studied. The findings showed that ionic product lixiviated from 45S5 bioactive glass, rich in silicon species and sodium ion, catalyzes a phase transition from β-TCP to Si-TCP by replacement of phosphorus for silicon and contributes to the improvement of scaffolds mechanical properties. The compressive strength of β-TCP/5%-BG and β-TCP/7.5%-BG was improved around 200% in comparison to pure β-TCP. Osteoblast-like cells (MG 63) were exposed to the materials for 24h through the use of medium conditioned by β-tricalcium phosphate/bioactive glass. Cell viability was measured by MTT assay in the cells and the data obtained were submitted to ANOVA, Tukey׳s multiple comparison (p<0.05). The β-TCP/7.5-BG promoted an increase of cell proliferation. The results suggest that compositions and processing method studied may provide appropriate materials for tissue engineering.

show abstract

Section: 4supporting

confidence: 65%

Hierarchical structures of β-TCP/45S5 bioglass hybrid scaffolds prepared by gelcasting

Lopes

Magalhães

Gouveia

et al. 2016

Journal of the Mechanical Behavior of Biomedical Materials

Self Cite

View full text Add to dashboard Cite

show abstract

“…α-tricalcium phosphate is commonly produced by thermal transition of a precursor with Ca/P ratio E1.5 [9][10][11] or by solid state reaction of a mixture of solid precursors [12][13][14][15]. The preparation of alpha-tricalcium phosphate by solid state reaction was also developed by our research group [16][17][18] Generally, by milling the solid phase in wet or dry conditions, it is possible to modify the particle size and hence the specific surface area of cement reactants and to control the mechanical properties of cement.…”

Section: Introductionmentioning

confidence: 99%

Calcium phosphate cements based on alpha-tricalcium phosphate obtained by wet method: Synthesis and milling effects

Thürmer

Diehl

Santos

2016

Ceramics International

View full text Add to dashboard Cite

Apatite bone cement reinforced with calcium silicate fibers

Motisuke

Santos

Bazanini

et al. 2014

J Mater Sci: Mater Med

View full text Add to dashboard Cite

Several research efforts have been made in the attempt to reinforce calcium phosphate cements (CPCs) with polymeric and carbon fibers. Due to their low compatibility with the cement matrix, results were not satisfactory. In this context, calcium silicate fibers (CaSiO3) may be an alternative material to overcome the main drawback of reinforced CPCs since, despite of their good mechanical properties, they may interact chemically with the CPC matrix. In this work CaSiO3 fibers, with aspect ratio of 9.6, were synthesized by a reactive molten salt synthesis and used as reinforcement in apatite cement. 5 wt.% of reinforcement addition has increased the compressive strength of the CPC by 250% (from 14.5 to 50.4 MPa) without preventing the cement to set. Ca and Si release in samples containing fibers could be explained by CaSiO3 partial hydrolysis which leads to a quick increase in Ca concentration and in silica gel precipitation. The latter may be responsible for apatite precipitation in needle like form during cement setting reaction. The material developed presents potential properties to be employed in bone repair treatment.

show abstract

Si-TCP synthesized from "Mg-free" reagents employed as calcium phosphate cement

Cited by 8 publications

References 23 publications

Hierarchical structures of β-TCP/45S5 bioglass hybrid scaffolds prepared by gelcasting

Hierarchical structures of β-TCP/45S5 bioglass hybrid scaffolds prepared by gelcasting

Calcium phosphate cements based on alpha-tricalcium phosphate obtained by wet method: Synthesis and milling effects

Apatite bone cement reinforced with calcium silicate fibers

Contact Info

Product

Resources

About