Microstructure development on sintered Ti/HA biocomposites produced by powder metallurgy

Balbinotti, Pedro; Gemelli, Enori; Buerger, Gabriel; Lima, Sarah Amin de; Jesus, Jailson de; Camargo, Nelson Heriberto Almeida; Henriques, Vinícius André Rodrigues; Soares, Glória Dulce de Almeida

doi:10.1590/s1516-14392011005000044

Cited by 43 publications

(42 citation statements)

References 21 publications

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“…1.3), and the flake-like microstructure was repeatedly associated with the production of OCP crystals. [70][71][72][73] Ca/P ratios increased constantly after four, six and eight weeks, reaching values equal to 1.39, 1.42 and 1.46, respectively. The sub-layer exhibited a Ca/P ratio of 1.51 after six weeks.…”

Section: Suspensionsmentioning

confidence: 95%

Induction suspension plasma sprayed biological-like hydroxyapatite coatings

Loszach

Gitzhofer

2015

J Biomater Appl

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Substituted hydroxyapatite coatings with different ions (Mg, Na, K, Cl, F) have been developed by the induction suspension plasma spray process. Suspensions were prepared with sol-gel. The main objective of this study was to demonstrate that induction suspension plasma spray technology possesses high material composition flexibility that allows as-sprayed coatings to closely mimic natural bone composition. Long-term in vitro behaviour of as-sprayed substituted coatings was evaluated with simulated body fluid. Data on the suspensions showed the formation of a pure hydroxyapatite phase. Transmission electron microscopy characterized various preparation stages of the suspensions. As-sprayed samples were distinguished by X-ray diffraction and scanning electron microscopy. Substituted elements were quantified by neutron activation. A well-crystallized hydroxyapatite phase was produced with concentration in various substitutions very close to natural bone composition. Ca/P and (Ca + Mg + Na + K)/P ratios provided evidence of the introduction of different cations into apatite structures. The immersion of samples into simulated body fluid led to the nucleation and growth of a flake-like octacalcium phosphate crystal layer at the surface of as-sprayed coatings after one week. Proof of octacalcium phosphate transformation and its partial dissolution and direct re-precipitation into apatite was disclosed by local energy dispersive spectroscopy and microstructure observation. Formation of a Ca/P ratio gradient from the precipitated layer surface to the as-sprayed coatings interface was observed after four weeks once the octacalcium phosphate crystals reached a critical size, resulting in the formation of a rich apatite layer at the interface after six weeks. A set of mechanisms has been proposed to explain these findings.

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Section: Suspensionsmentioning

confidence: 95%

Induction suspension plasma sprayed biological-like hydroxyapatite coatings

Loszach

Gitzhofer

2015

J Biomater Appl

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“…In specimens of Ti-HA processed by powder metallurgy, the presence of a compact layer on the surface of original Ti particles, consisting in a mixture of Ti x P y and CaTiO 3 phases, could be observed (Balbinotti et al, 2011).…”

Section: Analysis Of Bulk Materials 351 Fracture Surfacesmentioning

confidence: 98%

“…To improve the bioactivity and osseointegration of these structures, hydroxyapatite (HA) is often used, in addition to the base material. Although the biocompatibility of porous Ti-HA composites is well-assessed (Balbinotti et al, 2011;Ning et al, 2002), the bioactivity of future implant depends on the surface chemistry, as resulting from the decomposition of HA and subsequent interaction with Ti during processing. From this point of view, processing technologies and/or parameters that imply a low decomposition degree of HA are very interesting for the end application.…”

Section: Introductionmentioning

confidence: 99%

Selective laser melting of Ti6Al7Nb with hydroxyapatite addition

Marcu

Menapace

Girardini³

et al. 2014

Rapid Prototyping Journal

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Purpose -The purpose of this paper was to obtain by means of selective laser melting and then characterize biocomposites of medical-grade Ti6Al7Nb with hydroxyapatite (2 and 5 vol.%) and without hydroxyapatite, as reference. Design/methodology/approach -Rectangular samples were manufactured with the same scanning strategy; the laser power was between 50 W and 200 W. Processed samples were analysed by means of optical microscopy, scanning electron microscopy and microhardness. Findings -The results showed that despite the very short processing times, hydroxyapatite decomposed and interacted with the base Ti6Al7Nb material. The decomposition degree was found to depend on the applied laser power. From the porosity and bulk microstructure point of view, the most appropriate materials for the purposed medical applications were Ti6Al7Nb with hydroxyapatite processed with a laser power of 50 W. Originality/value -The originality of the present work consists in the study of the behaviour and interaction of hydroxyapatite additive with the Ti6Al7Nb base powder under selective laser melting conditions, as depending on the applied laser power.

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“…The researchers found that nanoscale materials have a higher osteoblast adhesion rate and can promote osteoblast function, which is beneficial to tissue growth after transplantation [1,83,92]. Balbinotti et al revealed that the nano-HA has smaller agglomeration and more uniform distribution in the composite, which results in the formation of more uniform Ca-P deposition in the simulated body fluid [89]. Although there were complex reactions between HA and Titanium during high temperature sintering, the formation of Ti 2 O, CaO, etc., also promoted the nucleation of apatite and increased biological activity of composites [21].…”

Section: Performance Evaluation Of Titanium Alloy/ha Compositesmentioning

confidence: 99%

Research Progress Regarding Interfacial Characteristics and the Strengthening Mechanisms of Titanium Alloy/Hydroxyapatite Composites

Jiang

Shao

et al. 2018

Materials

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Titanium alloy/Hydroxyapatite (HA) composites have become a hot research topic in biomedical materials, while there are some challenges concerning bioactivity and mechanical properties such as low interface adhesion at the interface between metal and ceramic, complex interfacial reactions, and so on. Nevertheless, composites with reinforced phases can reach special properties that meet the requirements of biomedical materials due to the strong interfacial interactions between reinforcing phases (nano-carbon, partial oxides, and so on) and Titanium alloys or HA. This review summarizes the interface properties and mechanisms of Titanium alloy/HA composites, including interfacial bonding methods, strengthening and toughening mechanisms, and performance evaluation. On this basis, the interface characteristics and mechanisms of the Titaniumalloy/HA composites with enhanced phase are prospected. The results show that the interfacial bonding methods in the Titanium alloy/HA composites include chemical reactions and mechanical effects. The strengthening and toughening mechanisms contain grain refinement strengthening, second phase strengthening, solution strengthening, cracks and pulling out mechanisms, etc. This review provides a guidline for the fabrication of biocomposites with both mechanical properties and bioactivity.

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Microstructure development on sintered Ti/HA biocomposites produced by powder metallurgy

Cited by 43 publications

References 21 publications

Induction suspension plasma sprayed biological-like hydroxyapatite coatings

Induction suspension plasma sprayed biological-like hydroxyapatite coatings

Selective laser melting of Ti6Al7Nb with hydroxyapatite addition

Research Progress Regarding Interfacial Characteristics and the Strengthening Mechanisms of Titanium Alloy/Hydroxyapatite Composites

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