Evaluation of microstructural parameters of human dentin by digital image analysis

Abstract

Digital image analysis was used to fully characterize the microstructure of human dentin. With the automatic routine implemented, field and region parameters related to human dentin characterization were obtained in significant statistical quantities. The results obtained for the density, area fraction, distance between neighbors, tilt angle, area and average diameter of the dentinary tubules are presented for unerupted third molars. The results, grouped per class of dentin or per tooth, are discussed in the light of the previous data found on the literature

Demineralized Dentin Matrix as a Carrier of Recombinant Human Bone Morphogenetic Proteins: <i>in Vivo</i> Study

“…The acid treatment of dentin might have increased the volume fraction (porosity) occupied by the dentinal tubules from an average porosity of 3.47 ± 1.46% to more than 5.88 ± 2.24% that is very similar to that of natural human bone (6.2%) 11,12) . Collagenolytic resorption by enzymes or osteoclasts increased surface area and porosity that accounts for triggering of the induction cascade by releasing of endogenous growth factors in DDM which induce phenotypic transformation of fi broblasts (Fig.…”

“…The number of dentin tubules is 18,000-21,000 tubules/mm 2,10) . They are more numerous in the inner third layer than the outer third layer of the dentin with the volume fraction (porosity) of average 3.47 ± 1.46% that is lesser than that of the natural human bone (6.2%) [11][12][13] .…”

Understanding Nano-Anatomy of Healthy and Carious Human Teeth: a Prerequisite for Nanodentistry

“…The dentin region adjacent to the DEJ, sometimes termed mantle dentin, contains only few tubules and practically no peri-tubular dentin [12], and lower mineral content [11]. Because mantle dentin exhibits lower mineralization and higher collagen content [18] than bulk dentin, the DEJ is tougher than bulk dentin or enamel [16].…”

“…Dentin abuts on dental enamel and acts as energy-absorbing, crackresistant structure [6]. Much effort has been devoted to understand the detailed composition and the microstructure of tubules [7][8][9][10][11][12], as well as their relationship to fracture toughness [6,13]. The interface between dentin and enamel, i.e.…”

The Tooth

“…26]. Nevertheless, a similar study of teeth from Brazilian donors reported a constant lumen diameter over the crown depth [27]. There are two consequences of these findings to consider.…”