Characterization of calcium phosphate coating and zinc incorporation on the porous alumina scaffolds

Abstract

Bone ingrowth requires materials with the existence of open and interconnected pores with diameters larger than 150 µm for proper circulation of nutrients. Such materials must possess enough mechanical strength to avoid failure whilst offering a bioactive surface for bone regeneration. We have developed porous ceramic alumina scaffold with compressive strength that achieves 3.3 MPa by replication method by using the network structure of cellular polymer foam. However, the biocompatibility of ceramics based on Al 2 O 3 requires further improvement so that it could have strong bonding to natural bone tissue. To address this problem of the interface between alumina and bone, we have developed a novel calcium phosphate with Zn 2+ (CaP-Zn) coating onto porous alumina ceramic scaffold by impregnating with calcium phosphate/poly(vinyl alcohol) slurry. The tri-dimensional alumina scaffold coated with CaP-Zn was extensively characterized by SEM, EDS and FTIR.

<p>Culture of dental pulp stem cells on nanoporous alumina substrates modified by carbon nanotubes</p>

“…44 Figure 1B shows the peaks at 2,924 and 2,854 (C-H), 1,630 (C=C) and 1,620 (COO − ) cm −1 . 45,46 The carboxylates groups of the MWCNT are bonded to the hydroxyl alumina. 47,48 Figure 2A-D shows SEM images and data EDAX of the FA and NAMC substrate.…”

Assessment of bone morphogenic protein and hydroxyapatite–titanium dioxide composites for bone implant materials

“…All obtained peaks are characteristic of the HAp. The weaker bands at 1454-1414 and 1644 cm − 1 [39] correspond to the CO 3 2 − in acetate. The characteristic OH − absorption peak of HAp is observed at 3575 cm − 1 and the peak at 1650 cm − 1 is attributed to absorbed water.…”

Microfabrication of complex porous tissue engineering scaffolds using 3D projection stereolithography

“…Following the fabrication procedure, scaffolds were removed from the stage and gently washed using PBS. Calcium carbonate residues were removed by rinsing the scaffolds in HCl (0.01 M, Sigma) solution for 24 h prior to cell seeding [47,48] (Fig. 1H).…”