In Vitro studies of bioactive glass/polyhydroxybutyrate composites

Paiva, André Oliveira; Duarte, M.G.G.M.; Fernandes, María Helena; Gil, Maria Helena; Costa, Necesio

doi:10.1590/s1516-14392006000400013

Cited by 22 publications

(5 citation statements)

References 22 publications

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“…The minimum Si in the case of 28 days of SBF soaking indicates the fully covered surface by CaO P 2 O 5 rich films and/or HCA. After 28 days of SBF soaking, the Ca/P molar ratio of samples is similar to the 1.0 2.0 range of the value present in human body [28,29]. The characteristic bonds of glass are revealed with the Si O Si and P O vibrational peaks in FTIR spectra.…”

Section: Bioactivity Of 3dom Bgsupporting

confidence: 60%

In vitro bioactivity and stem cells attachment of three-dimensionally ordered macroporous bioactive glass incorporating iron oxides

Charoensuk

Sirisathitkul

Boonyang

et al. 2016

Journal of Non-Crystalline Solids

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Three dimensionally ordered macroporous bioactive SiO 2 CaO Na 2 O P 2 O 5 glass (3DOM BG) is synthesized by using the sol gel method. After an in vitro test in simulated body fluid (SBF), the hydroxyapatite (HAp) crystalline phase is clearly formed on its surface as confirmed by X ray diffractometry (XRD) and Raman spectroscopy. Mag netic 3DOM BG/Fe samples are synthesized by partial substitution of SiO 2 with iron oxide. Whilst the HAp layer is not confirmed, energy dispersive spectroscopy (EDS), Fourier transform infrared spectroscopy (FTIR) and XRD analysis reveal calcium phosphate layer on the surface of 3DOM BG/Fe samples after the SBF soaking. The growth of HAp like layer is slower with increasing iron oxides. The initial mechanism that thought to induce bone forma tion is reduced due to the replacement of Ca 2+ with Fe ions in the glass network. The formation of HAp like layer is modified by the sedimentation of Ca and P while the nonmagnetic 3DOM BG forms the calcium phosphate by the ionic exchange following the Hench mechanism. The adult human adipose tissue derived stem cells (hADSCs) can be closely attached and well spread on the flat plate of all 3DOM BG/Fe and 3DOM BG. Without detectable cytotoxicity possibly induced by iron oxides, the osteoblast can be grown and proliferated. In addition to these bioactivity and biocompatibility, porous structures can allow their possible use in targeted drug delivery and magnetic properties of 3DOM BG/Fe can essentially be implemented in hyperthermia therapy.

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Section: Bioactivity Of 3dom Bgsupporting

confidence: 60%

In vitro bioactivity and stem cells attachment of three-dimensionally ordered macroporous bioactive glass incorporating iron oxides

Charoensuk

Sirisathitkul

Boonyang

et al. 2016

Journal of Non-Crystalline Solids

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“…The degradation rate of P(3HB) is quite slow compared to Polyα‐hydroxyacids . The degradation of P(3HB) occurs initially by hydrolysis and releases carbon dioxide and water …”

Section: Biodegradable Polymers‐bg Compositesmentioning

confidence: 99%

Bioglass® 45S5‐based composites for bone tissue engineering and functional applications

Rizwan

Hamdi

Basirun

2017

J Biomedical Materials Res

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Bioglass® 45S5 (BG) has an outstanding ability to bond with bones and soft tissues, but its application as a load-bearing scaffold material is restricted due to its inherent brittleness. BG-based composites combine the amazing biological and bioactive characteristics of BG with structural and functional features of other materials. This article reviews the composites of Bioglass in combination with metals, ceramics and polymers for a wide range of potential applications from bone scaffolds to nerve regeneration. Bioglass also possesses angiogenic and antibacterial properties in addition to its very high bioactivity; hence, composite materials developed for these applications are also discussed. BG-based composites with polymer matrices have been developed for a wide variety of soft tissue engineering. This review focuses on the research that suggests the suitability of BG-based composites as a scaffold material for hard and soft tissues engineering. Composite production techniques have a direct influence on the bioactivity and mechanical behavior of scaffolds. A detailed discussion of the bioactivity, in vitro and in vivo biocompatibility and biodegradation is presented as a function of materials and its processing techniques. Finally, an outlook for future research is also proposed. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 3197-3223, 2017.

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“…However, there are stringent requirements and issues on the preparation of the bioactive glass powder feedstock in order to ensure the composition uniformity. The bioactive glass powders are often prepared through the melt quenching process, which involves a series of preparation steps, including milling, drying, melting, quenching, crushing, drying, grinding, and sieving ( Ref 8,11). In addition, contamination can be introduced during the lengthy procedures such as milling, crushing, and grinding.…”

Section: Introductionmentioning

confidence: 99%

Bioactive Glass-Ceramic Coatings Synthesized by the Liquid Precursor Plasma Spraying Process

et al. 2010

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In this study, the liquid precursor plasma spraying process was used to manufacture P 2 O 5 -Na 2 O-CaOSiO 2 bioactive glass-ceramic coatings (BGCCs), where sol and suspension were used as feedstocks for plasma spraying. The effect of precursor and spray parameters on the formation and crystallinity of BGCCs was systematically studied. The results indicated that coatings with higher crystallinity were obtained using the sol precursor, while nanostructured coatings predominantly consisting of amorphous phase were synthesized using the suspension precursor. For coatings manufactured from suspension, the fraction of the amorphous phase increased with the increase in plasma power and the decrease in liquid precursor feed rate. The coatings synthesized from the suspension plasma spray process also showed a good in vitro bioactivity, as suggested by the fast apatite formation when soaking into SBF.

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In Vitro studies of bioactive glass/polyhydroxybutyrate composites

Cited by 22 publications

References 22 publications

In vitro bioactivity and stem cells attachment of three-dimensionally ordered macroporous bioactive glass incorporating iron oxides

In vitro bioactivity and stem cells attachment of three-dimensionally ordered macroporous bioactive glass incorporating iron oxides

Bioglass® 45S5‐based composites for bone tissue engineering and functional applications

Bioactive Glass-Ceramic Coatings Synthesized by the Liquid Precursor Plasma Spraying Process

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