2010
DOI: 10.1590/s1516-05722010000200016
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Avaliação da atividade antibacteriana e prospecção fitoquímica de Solanum paniculatum Lam. e Operculina hamiltonii (G. Don) D. F. Austin & Staples, do semi-árido paraibano

Abstract: RESUMO:Devido ao aparecimento de populações de parasitos resistentes, as drogas farmacêuticas, alternativas de controle, estão sendo pesquisadas utilizando plantas medicinais. O objetivo deste estudo foi avaliar a atividade antibacteriana e realizar a análise fitoquímica do extrato etanólico de duas espécies do semi-árido paraibano, Solanum paniculatum Lam. e Operculina hamiltonii (G. Don) D. F. Austin & Staples. As referidas espécies são muito utilizadas pela população rural contra verminoses gastrintestinais… Show more

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Cited by 24 publications
(21 citation statements)
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“…Flavonoids, alkaloids, triterpenes, sesquiterpenes, tannins, and lignans have been extensively studied and found to possess these properties. Studies have reported the presence of these and other active compounds in various plants, in both plant and root extracts (Lôbo et al, 2010). Thus, it is important to consider that the rhizosphere has a high concentration of organic nutrients derived from the roots, influencing microorganisms to produce similar compounds (Melo and Azevedo, 2008).…”
Section: Discussionmentioning
confidence: 99%
“…Flavonoids, alkaloids, triterpenes, sesquiterpenes, tannins, and lignans have been extensively studied and found to possess these properties. Studies have reported the presence of these and other active compounds in various plants, in both plant and root extracts (Lôbo et al, 2010). Thus, it is important to consider that the rhizosphere has a high concentration of organic nutrients derived from the roots, influencing microorganisms to produce similar compounds (Melo and Azevedo, 2008).…”
Section: Discussionmentioning
confidence: 99%
“…As classes de metabólitos presentes nas amostras, como esteroides/ triterpenoides, flavonoides e alcaloides, apresentam significativo potencial antibacteriano 6 . os resultados demonstraram atividade bacteriostática dos frutos maduros de Solanum sp.…”
Section: Discussionunclassified
“…os resultados demonstraram atividade bacteriostática dos frutos maduros de Solanum sp. frente à bactéria MRSA, ação que pode ser exercida pelos metabólitos secundários avaliados na triagem fitoquímica 6 . Substâncias com possível ação antibacteriana estão presentes nas frações diclorometano e hidroetanólica, as mesmas apresentaram menor CIM, dentre as amostras avaliadas.…”
Section: Discussionunclassified
“…Several Solanum species are cited in the literature to possess antimicrobial activity against fungi, bacteria and mycobacteria (Bontempo et al, 2013;Balachandran et al, 2012, Das et al, 2010Lozoya et al, 1992). S. paniculatum had activity against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa (Lôbo et al, 2010) but, to the best of our knowledge, no studies concerning the antimicrobial activity of S. guaraniticum have been reported. Thus, the aim of this study was to evaluate the in vitro antimicrobial and antimycobacterial activities of the crude extract (CE), chloroform (CHCl 3 ), ethyl acetate (AcOEt) and butanol (BuOH) fractions of the S. guaraniticum leaves, against Grampositive, Gram-negative bacteria, fungi and mycobacteria, by broth microdilution method to achieve the minimum inhibitory concentration (MIC), in order to verify their possible potential in the treatment of infectious diseases.…”
Section: Introductionmentioning
confidence: 99%