Genetic parameters for body weight, carcass chemical composition and yield in a broiler-layer cross developed for QTL mapping

Nunes, Beatriz do Nascimento; Ramos, Salvador Boccaletti; Savegnago, Rodrigo Pelicioni; Ledur, Mônica Corrêa; Nones, Kátia; Klein, Cátia Silene; Munari, Danísio Prado

doi:10.1590/s1415-47572011005000019

Cited by 9 publications

(6 citation statements)

References 21 publications

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“…The largest phenotypic correlations were between DW and EW and between DW and HEW, while the genetic correlation between BW42 and DP was small (0.39). Nunes et al [17] estimated the genetic parameters related to body weight, chemical carcass composition, and yield in a broiler-layer cross and found a genetic correlation between BW42 and DP of 0.33, which was in accord with the current results. We found highly positive genetic (0.74) and phenotypic correlations (0.63) between BW42 and BMW.…”

Section: Discussionsupporting

confidence: 83%

“…Xu [16] previously estimated that breast muscle weight (BMW) and breast muscle weight percentage (BMWP) had moderate heritabilities (0.23 and 0.16, respectively), while the heritability of body weight was high (0.48). Furthermore, the heritability of BW42 in broilers in Nunes’ study was 0.31 [17]. Compared with these results, we found similar heritabilities of most traits, other than BMW.…”

Section: Discussionsupporting

confidence: 67%

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Genome-wide association study reveals novel loci associated with body size and carcass yields in Pekin ducks

et al. 2019

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BackgroundPekin duck products have become popular in Asia over recent decades and account for an increasing market share. However, the genetic mechanisms affecting carcass growth in Pekin ducks remain unknown. This study aimed to identify quantitative trait loci affecting body size and carcass yields in Pekin ducks.ResultsWe measured 18 carcass traits in 639 Pekin ducks and performed genotyping using genotyping-by-sequencing (GBS). Loci-based association analysis detected 37 significant loci for the 17 traits. Thirty-seven identified candidate genes were involved in many biological processes. One single nucleotide polymorphism (SNP) (Chr1_140105435 A > T) located in the intron of the ATPase phospholipid transporting 11A gene (ATP11A) attained genome-wide significance associated with five weight traits. Eight SNPs were significantly associated with three body size traits, including the candidate gene plexin domain containing 2 (PLXDC2) associated with breast width and tensin 3 (TNS3) associated with fossil bone length. Only two SNPs were significantly associated with foot weight and four SNPs were significantly associated with heart weight. In the gene-based analysis, three genes (LOC101791418, TUBGCP3 (encoding tubulin gamma complex-associated protein 3), and ATP11A) were associated with four traits (42-day body weight, eviscerated weight, half-eviscerated weight, and leg muscle weight percentage). However, no loci were significantly associated with leg muscle weight in this study.ConclusionsThe novel results of this study improve our understanding of the genetic mechanisms regulating body growth in ducks and thus provide a genetic basis for breeding programs aimed at maximizing the economic potential of Pekin ducks.Electronic supplementary materialThe online version of this article (10.1186/s12864-018-5379-1) contains supplementary material, which is available to authorized users.

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Section: Discussionsupporting

confidence: 83%

Section: Discussionsupporting

confidence: 67%

Genome-wide association study reveals novel loci associated with body size and carcass yields in Pekin ducks

et al. 2019

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“…Phenotypic and genetic correlations of the carcass composition traits were previously presented by Nunes et al . () using a larger number of F 2 individuals from reciprocally crossing the same parental lines used here. Body weight at 6 weeks had positive phenotypic and genetic correlations with fat content in the carcass (0.38 and 0.46, respectively), and negative phenotypic and genetic correlations with protein (−0.37 and −0.45) and ash (−0.33 and −0.46) content.…”

Section: Resultsmentioning

confidence: 99%

Quantitative trait loci associated with chemical composition of the chicken carcass

Nones¹,

Ledur

Zanella

et al. 2012

Animal Genetics

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Major objectives of the poultry industry are to increase meat production and to reduce carcass fatness, mainly abdominal fat. Information on growth performance and carcass composition are important for the selection of leaner meat chickens. To enhance our understanding of the genetic architecture underlying the chemical composition of chicken carcasses, an F(2) population developed from a broiler × layer cross was used to map quantitative trait loci (QTL) affecting protein, fat, water and ash contents in chicken carcasses. Two genetic models were applied in the QTL analysis: the line-cross and the half-sib models, both using the regression interval mapping method. Six significant and five suggestive QTL were mapped in the line-cross analysis, and four significant and six suggestive QTL were mapped in the half-sib analysis. A total of eleven QTL were mapped for fat (ether extract), five for protein, four for ash and one for water contents in the carcass using both analyses. No study to date has reported QTL for carcass chemical composition in chickens. Some QTL mapped here for carcass fat content match, as expected, QTL regions previously associated with abdominal fat in the same or in different populations, and novel QTL for protein, ash and water contents in the carcass are presented here. The results described here also reinforce the need for fine mapping and to perform multi-trait analyses to better understand the genetic architecture of these traits.

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“…In the same population (Embrapa F 2 Chicken Resource Population), pedigree-based heritability for ABF was estimated at 0.33 ± 0.19 in the F 2 -CTCT generation (layer males crossed with broiler females) and 0.82 ± 0.3 in the F 2 -TCTC generation (broiler males crossed with layer females) 28 . Considering the carcass fat content traits, heritability estimates for CFC expressed in percentage of wet carcass was 0.53 ± 0.10, and the heritability for fat percentage in dry-matter basis (CFCDM) was 0.55 ± 0.10, using records of 3,422 chickens 3 .…”

Section: Discussionmentioning

confidence: 99%

“…Modern commercial broiler chickens are produced from crosses that have been simultaneously selected for rapid growth, increased meat-production, and improved carcass yield 1 , 2 . However, chickens selected for higher body weight might exhibit increased appetite and excessive energy consumption, which may lead to excessive fat accumulation 3 – 5 .…”

Section: Introductionmentioning

confidence: 99%

Integration of genome wide association studies and whole genome sequencing provides novel insights into fat deposition in chicken

Moreira

Boschiero

Cesar

et al. 2018

Sci Rep

Self Cite

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Excessive fat deposition is a negative factor for poultry production because it reduces feed efficiency, increases the cost of meat production and is a health concern for consumers. We genotyped 497 birds from a Brazilian F2 Chicken Resource Population, using a high-density SNP array (600 K), to estimate the genomic heritability of fat deposition related traits and to identify genomic regions and positional candidate genes (PCGs) associated with these traits. Selection signature regions, haplotype blocks and SNP data from a previous whole genome sequencing study in the founders of this chicken F2 population were used to refine the list of PCGs and to identify potential causative SNPs. We obtained high genomic heritabilities (0.43–0.56) and identified 22 unique QTLs for abdominal fat and carcass fat content traits. These QTLs harbored 26 PCGs involved in biological processes such as fat cell differentiation, insulin and triglyceride levels, and lipid biosynthetic process. Three of these 26 PCGs were located within haplotype blocks there were associated with fat traits, five overlapped with selection signature regions, and 12 contained predicted deleterious variants. The identified QTLs, PCGs and potentially causative SNPs provide new insights into the genetic control of fat deposition and can lead to improved accuracy of selection to reduce excessive fat deposition in chickens.

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Genetic parameters for body weight, carcass chemical composition and yield in a broiler-layer cross developed for QTL mapping

Cited by 9 publications

References 21 publications

Genome-wide association study reveals novel loci associated with body size and carcass yields in Pekin ducks

Genome-wide association study reveals novel loci associated with body size and carcass yields in Pekin ducks

Quantitative trait loci associated with chemical composition of the chicken carcass

Integration of genome wide association studies and whole genome sequencing provides novel insights into fat deposition in chicken

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