Population and mutation analysis of Y-STR loci in a sample from the city of São Paulo (Brazil)

Soares-Vieira, José Arnaldo; Billerbeck, Ana Elisa C.; Iwamura, Edna Sadayo Miazato; Mendonca, Berenice B.; Gusmão, Leonor; Otto, Paulo Alberto

doi:10.1590/s1415-47572008000400009

Cited by 10 publications

(3 citation statements)

References 21 publications

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“…Forensic genetics interest has focused on Y-STR markers, which are available for population genetic, evolutionary, genealogical, and forensic investigations (Soares- Vieira et al, 2008). The results reported here characterized the genetic diversity of the population of Goias based on Y-STR and contributed to consolidate a database that could be useful in human identification studies.…”

Section: Resultsmentioning

confidence: 90%

Short Communication Y-STR haplotype diversity and population data for Central Brazil: implications for environmental forensics and paternity testing

et al. 2014

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ABSTRACT. The central region of Brazil was colonized by internal migration of individuals of different origins, who contributed to the genetic diversity existing in this population. This study determined the allele frequencies and haplotype diversity of Y-STRs in Goiás State, Central Brazil, and compared the data obtained with a sample of the Brazilian population, consisting of individuals from the five geographical regions of Brazil. A total of 353 males were typed for Y-STR haplotype diversity in Central Brazil 12 Y-chromosome short tandem repeat (Y-STR) markers. We selected males who had no degree of relatedness, from the five mesoregions of Goiás State. DNA was extracted from blood samples followed by the amplification of the 12 Y-chromosome loci. The products were analyzed to obtain the allele profiles on an ABI3500 automated sequencer using the Gene Mapper software. Allele frequencies and haplotype diversity were estimated by direct counting, and gene diversity for each locus was computed using the Arlequin software. The results are consistent with the history of miscegenation of the population of Central Brazil, in which we observed 321 different haplotypes. The average gene diversity at the 12 loci was 0.645. DYS385b and DYS389I showed the highest (0.704) and lowest (0.520) genetic diversity values, respectively. The F ST value between the Brazilian and Goiás populations was 0.00951, showing no statistical significance. The results of this study allowed the establishment of haplotypes found in the forensic samples of Goiás State serving as a reference in the elucidation of criminal cases and paternity tests, as well as population and evolutionary inferences.

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Section: Resultsmentioning

confidence: 90%

Short Communication Y-STR haplotype diversity and population data for Central Brazil: implications for environmental forensics and paternity testing

et al. 2014

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“…In Brazil, considerable research effort has been directed towards improved genetic identification from complex samples such as exhumed bones and other challenging biological material, 36 as well as to frequency studies of DNA markers in the Brazilian population that can be used in calculations of probability. 37 Hardtissue specimens recovered from the thirty skeletons of indigent people described above were investigated in a combined histological and DNA analysis conducted in collaboration with the Laboratory of Molecular Pathology in the Department of Pathology-Escola Paulista de Medicina/Federal University of São Paulo. This was intended to improve understanding of post-mortem diagenesis and to develop applications for DNA analysis of skeletal specimens from tropical soils, in order to optimise genetic and anthropological protocols 38 -as well as those involving other physico-chemical approaches.…”

Section: Humanmentioning

confidence: 99%

Procedural and political aspects of forensic exhumation in Brazil

Guimarães¹,

Francisco²,

Evison

et al. 2017

Human Remains and Violence: An Interdisciplinary Journal

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Exhumation may be defined as the legally sanctioned excavation and recovery of the remains of lawfully buried or – occasionally – cremated individuals, as distinct from forensic excavations of clandestinely buried remains conducted as part of a criminal investigation and from unlawful disinterment of human remains, commonly referred to as bodysnatching. The aim of this article is to review the role of exhumation – so defined – in the activities of CEMEL, the Medico-Legal Centre of the Ribeirão Preto Medical School-University of São Paulo, in international, regional and local collaborations. Exhumations form part of routine forensic anthropology casework; scientific research in physical and forensic anthropology; and forensic casework conducted in collaboration with the Brazilian Federal Police; and are carried out as part of humanitarian investigations into deaths associated with the civil–military dictatorship of 1964 to 1985. This article aims to offer a non-technical summary – with reference to international comparative information – of the role of exhumation in investigative and scientific work and to discuss developments in their historical and political context.

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“…37 Hardtissue specimens recovered from the thirty skeletons of indigent people described above were investigated in a combined histological and DNA analysis conducted 39 for example, described procedures for the genetic investigation of bones from individual exhumations. These procedures were also shown to be useful for individual exhumations in which the objective was the investigation of vital reactions related to the cause of death using scanning electron microscopy.…”

Section: Scientific Research In Physical and Forensic Anthropologymentioning

confidence: 99%

Forensic investigation, truth and trust in the context of transitional justice in Brazil

Guimarães¹,

Francisco²,

Garcia³

et al. 2017

Human Remains and Violence: An Interdisciplinary Journal

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Exhumation may be defined as the legally sanctioned excavation and recovery of the remains of lawfully buried or -occasionally -cremated individuals, as distinct from forensic excavations of clandestinely buried remains conducted as part of a criminal investigation and from unlawful disinterment of human remains, commonly referred to as 'bodysnatching'. The aim of this article is to review the role of exhumation -so defined -in the activities of CEMEL, the Medico-Legal Centre of the Ribeirão Preto Medical School-University of São Paulo, in international, regional and local collaborations. Exhumations form part of routine forensic anthropology casework; scientific research in physical and forensic anthropology; and forensic casework conducted in collaboration with the Brazilian Federal Police; and are carried out as part of humanitarian investigations into deaths associated with the civil-military dictatorship of 1964 to 1985. This article aims to offer a non-technical summary -with reference to international comparative information -of the role of exhumation in investigative and scientific work and to discuss developments in their historical and political context.

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Population and mutation analysis of Y-STR loci in a sample from the city of São Paulo (Brazil)

Cited by 10 publications

References 21 publications

Short Communication Y-STR haplotype diversity and population data for Central Brazil: implications for environmental forensics and paternity testing

Short Communication Y-STR haplotype diversity and population data for Central Brazil: implications for environmental forensics and paternity testing

Procedural and political aspects of forensic exhumation in Brazil

Forensic investigation, truth and trust in the context of transitional justice in Brazil

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