Consensus of the Brazilian Society of Infectious Diseases on the management and treatment of hepatitis C

Araújo, Evaldo Stanislau Affonso de; Mendonça, João Silva de; Barone, Antonio; Gonçales, Fernando Lopes; Ferreira, Marcelo Simão; Focaccia, Roberto; Pawlotsky, Jean‐Michel

doi:10.1590/s1413-86702007000700001

Cited by 2 publications

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“…The most commonly used score for biopsy is the METAVIR fibrosis score, and treatment is indicated with a grade of at least F2. 64,67,68,72 –74 However, liver biopsy is not commonly performed in Vietnam. Instead noninvasive methods, that is, serological markers and ultrasound-based methods are used to assess liver fibrosis.…”

Section: Discussionmentioning

confidence: 99%

“…The standard treatment course currently recommended for chronic hepatitis C is the combination of pegylated interferon and ribavirin, for which a study reported an efficacy of 56% in achieving the sustained viral suppression. 72 Two options of pegylated interferon are available: pegylated interferon α-2a and pegylated interferon α-2b, which have similar rates of success.…”

Section: Discussionmentioning

confidence: 99%

“…Patients with HCV genotypes 1, 4, and 6 should receive 48 weeks of treatment, while genotypes 2 and 3 should receive 24 weeks of treatment. 72,89…”

Section: Discussionmentioning

confidence: 99%

“…During the treatment, the effectiveness is assessed using the following categories to predict a successful SVR. 72,89…”

Section: Discussionmentioning

confidence: 99%

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Epidemiology, Responses, and Way Forward

Sereno

Mesquita²,

Kato³

et al. 2012

Journal of the International Association of Physicians in AIDS

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Viral hepatitis is a disease of great concern to public health that is now met by a favorable momentum to combat the global epidemic. This article is intended to highlight the importance of viral hepatitis in the Vietnam population as well in the group of people living with HIV/AIDS (PLWHA). We reviewed available data on epidemiology and response on hepatitis B virus (HBV) and hepatitis C virus (HCV) and HIV coinfection in Vietnam. The hepatitis B surface antigen (HBsAg) prevalence in the general population ranged from 5.7% to 24.7%. The anti-HCV prevalence ranged from 0.38% to 4.3% in the general population, while among people who inject drugs (PWIDs) it ranged from 31% to 97.2%. The HBV prevalence among PLWHA is similar to the general population, while HCV/HIV coinfection is concentrated in some groups. Anti-HCV prevalence among HIV-infected PWIDs can be as high as 98.5%. Developing policies for diagnosis and treatment of chronic HBV and HCV infections are critical priorities in order to prevent clinical progression to cirrhosis and liver cancer.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Epidemiology, Responses, and Way Forward

Sereno

Mesquita²,

Kato³

et al. 2012

Journal of the International Association of Physicians in AIDS

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Correlation between salivary anti‐HCV antibodies and HCV RNA in saliva and salivary glands of patients with chronic hepatitis C

Caldeira

Silva

et al. 2012

J Oral Pathology Medicine

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Taken together, our results suggest that there is no correlation between the presence of anti-HCV antibodies in saliva and the detection of HCV RNA in saliva and salivary glands in patients with chronic hepatitis C. Nevertheless, as there was a statistically significant difference between detection of anti-HCV antibodies and HCV RNA in stimulated saliva, our study points toward the need for new research on mechanisms of HCV shedding in saliva.

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Consensus of the Brazilian Society of Infectious Diseases on the management and treatment of hepatitis C

Cited by 2 publications

References 0 publications

Epidemiology, Responses, and Way Forward

Epidemiology, Responses, and Way Forward

Correlation between salivary anti‐HCV antibodies and HCV RNA in saliva and salivary glands of patients with chronic hepatitis C

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