Spinal epidural abscess due to Mycobacterium tuberculosis in a patient with AIDS: case report and review of the literature

Metta, Humberto; Corti, Marcelo; Redini, Liliana; Yampolsky, Claudio; Schtirbu, Ricardo

doi:10.1590/s1413-86702006000200013

Cited by 17 publications

(3 citation statements)

References 7 publications

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“…7 However, many authors have reported SEA secondary to TB. 11 The present case, a cervical SEA without bony involvement in an HIV-pos-itive patient, is the first case in the reported literature to the best of our knowledge. TB osteitis of the spine (Pott disease) accounts for 1% of all TB infections.…”

Section: Discussionmentioning

confidence: 56%

Tubercular Epidural Abscess in Cervical Spine Without Bony Involvement in a Patient With HIV Coinfection

Pruthi

Majid

Pandey

et al. 2014

Neurosurgery Quarterly

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Spinal epidural abscess (SEA) represents a severe, generally pyogenic, infection of the epidural space, which compresses the neural elements and requires urgent surgical decompression to avoid permanent neurological deficit. Tubercular SEA without bony involvement is very rare and has not been reported in patients with human immunodeficiency virus (HIV) infection. We present a rare case of SEA of tubercular origin in the cervical spine without bony involvement in a patient with HIV infection. A 35-year-old HIV-positive female presented with neck pain, rapid-onset quadriparesis with urinary retention. Magnetic resonance imaging showed a cervical ventrally placed epidural collection enhancing on contrast, without bony involvement, suggestive of epidural abscess. The pus was drained through the anterior cervical approach. Histopathology revealed multiple acid-fast bacilli, suggestive of tubercular infection. The patient made an uneventful recovery after surgical decompression and antitubercular treatment. SEA due to tuberculosis in absence of bony involvement is extremely rare in patients with HIV Infection. Early diagnosis followed by urgent surgical decompression combined with antituberculous drugs lead to good outcome in these patients.

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Section: Discussionmentioning

confidence: 56%

Tubercular Epidural Abscess in Cervical Spine Without Bony Involvement in a Patient With HIV Coinfection

Pruthi

Majid

Pandey

et al. 2014

Neurosurgery Quarterly

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“…[20][21][22][23] Furthermore, most reports of spine surgery in HIV-positive patients do not pertain to degenerative spine conditions. 13,14,[24][25][26][27] As such, the need for greater investigation into the outcomes after surgery for LDD in HIV-positive patients is significant.…”

Section: Discussionmentioning

confidence: 99%

“…Contributing factors may include surgeon avoidance due to perceived increased risk of complications or viral transmission to surgeon or staff 20–23. Furthermore, most reports of spine surgery in HIV-positive patients do not pertain to degenerative spine conditions 13,14,24–27. As such, the need for greater investigation into the outcomes after surgery for LDD in HIV-positive patients is significant.…”

Section: Discussionmentioning

confidence: 99%

Surgical Outcomes of Human Immunodeficiency Virus–positive Patients Undergoing Lumbar Degenerative Surgery

Varshneya

Wadhwa

et al. 2021

Clinical Spine Surgery: A Spine Publication

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Objective: The objective of this study was to determine the postoperative complications and quality outcomes of the human immunodeficiency virus (HIV)-positive patients undergoing surgical management for lumbar degenerative disease (LDD).Methods: This study identified patients with who underwent surgery for LDD between 2007 and 2016. Patients were stratified based on whether they were HIV positive at the time of surgery. Multivariate regression was utilized to reduce the confounding of baseline covariates. Patients who underwent 3 or more levels of surgical correction were under the age of 18 years, or those with any prior history of trauma or tumor were excluded from this study. Baseline comorbidities, postoperative complication rates, and reoperation rates were determined.Results: A total of 120,167 patients underwent primary lumbar degenerative surgery, of which 309 (0.26%) were HIV positive. In multivariate regression analysis, the HIV-positive cohort was more likely to be readmitted at 30 days [odds ratio (OR) = 1.9, 95% confidence interval (CI): 1.2-2.8], 60 days (OR = 1.7, 95% CI: 1.2-2.5), and 90 days (OR = 1.5, 95% CI: 1.0-2.2). The HIVpositive cohort was also more likely to experience any postoperative complication (OR = 1.7, 95% CI: 1.2-2.3). Of the major drivers identified, HIV-positive patients had significantly greater odds of cerebrovascular disease and postoperative neurological complications (OR = 3.8, 95% CI: 1.8-6.9) and acute kidney injury (OR = 3.4, 95% CI: 1.3-7.1). Costs of index hospitalization were not significantly different between the 2 cohorts

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Neurological TB in HIV

Bovijn

Solomons

Marais³

2019

HIV and Tuberculosis

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Spinal epidural abscess due to Mycobacterium tuberculosis in a patient with AIDS: case report and review of the literature

Cited by 17 publications

References 7 publications

Tubercular Epidural Abscess in Cervical Spine Without Bony Involvement in a Patient With HIV Coinfection

Tubercular Epidural Abscess in Cervical Spine Without Bony Involvement in a Patient With HIV Coinfection

Surgical Outcomes of Human Immunodeficiency Virus–positive Patients Undergoing Lumbar Degenerative Surgery

Neurological TB in HIV

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