2005
DOI: 10.1590/s0482-50042005000400005
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Histopatologia e imunopatologia de glândulas salivares menores de pacientes com síndrome de Sjögren (SSj)

Abstract: A síndrome de Sjögren (SSj) é uma doença auto-imune com manifestações primárias nas glândulas salivares e lacrimais, sendo clinicamente caracterizada por secura oral (xerostomia) e ocular (xeroftalmia). É uma doença pro

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Cited by 14 publications
(6 citation statements)
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References 26 publications
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“…We have also observed a lower density of lingual salivary gland acini in chagasic patients compared to non-chagasic patients. Although a reduction in acinar density of salivary glands has already been described in other diseases such as diabetes 16 and Sjogren’s syndrome 17 , we did not find studies that evaluated the acin density of salivary glands in chagasic patients. However, we believe that the decrease in acinar density in chagasic patients was due to glandular acini hypertrophy that occupied a larger area of the tissue.…”
Section: Discussioncontrasting
confidence: 56%
“…We have also observed a lower density of lingual salivary gland acini in chagasic patients compared to non-chagasic patients. Although a reduction in acinar density of salivary glands has already been described in other diseases such as diabetes 16 and Sjogren’s syndrome 17 , we did not find studies that evaluated the acin density of salivary glands in chagasic patients. However, we believe that the decrease in acinar density in chagasic patients was due to glandular acini hypertrophy that occupied a larger area of the tissue.…”
Section: Discussioncontrasting
confidence: 56%
“…Histologicamente e estruturalmente, as glândulas salivares são formadas por elementos parenquimatosos revestidos e sustentados por tecido conjuntivo. Esses elementos são constituídos por um sistema de ductos e aglomerados de grãos denominados ácinos (BARCELLOS;ANDRADE, 2005).…”
Section: Introductionunclassified
“…A etiopatogenia da SS não é completamente esclarecida. No entanto, alguns estudos relatam que alterações tanto imunológicas quanto infecciosas e/ou genéticas, combinadas entre si, podem estar associadas ao desenvolvimento de alterações autoimunes (Barcellos;Andrade, 2005).…”
Section: Introductionunclassified