Piodermatite-pioestomatite vegetante: relato de caso e revisão de literatura

Abstract

Pyodermatitis-pyostomatitis vegetans is a rare inflammatory dermatosis of unknown etiology, with a typical mucocutaneous involvement. We report the case of a woman with pustular and vesicular lesions in the axillae, evolving with vegetating plaques and pustules with annular grouping. The disease progressed with vulvar and inguinal involvement as well as involvement of the oral, nasal and ocular mucous membranes. She started the treatment with prednisone (40 mg/day), with remission of the lesions after one month of use of such medication. Association with inflammatory bowel disease occurs in 70% of the cases. Immunofluorescence, which is typically negative, helps to characterize the disease. A rapid response to systemic steroids is expected.

Case for diagnosis

“…The etiology of PD-PSV is unknown, and its pathogenesis is poorly understood. 1,4,5 It is associated with gastrointestinal disease and has been described as a highly specific marker for inflammatory bowel diseases (IBD). 6,7 Diagnostic differentiation between PD-PSV and pemphigus vegetans is essential, even though immunosuppressant regimen would be similar.…”