Desafios no diagnóstico e tratamento de um caso de síndrome SAPHO na infância

This pathology is a rare and serious form of acne vulgaris. Its treatment is a challenge because it does not respond satisfactorily to traditional acne therapies. Its diagnosis must be early so that the appropriate therapy is instituted quickly, avoiding sequelae. The case reported is a young male patient with acneic lesions associated with systemic manifestations and laboratory abnormalities. Treatment with prednisone and oral antibiotic therapy is instituted. After weaning from corticosteroid therapy, oral isotretinoin was introduced in a stepwise dose. The patient progresses with improvement of active lesions and cicatricial lesions on the back. The Acne Fulminans is destructive, begins with acute pain, with abrupt development of acneic lesions, hemorrhagic nodules and ulcerations with necrotic background, associated with systemic manifestations. The diagnosis is clinical. Therapy should be aggressive, involving oral corticosteroids with isotretinoin. Dapsone is also used as an antiinflammatory agent.

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Demodicosis as treatment complication of amicrobial pustulosis of the folds

Jorge

Miguel

Braghiroli

et al. 2018

An. Bras. Dermatol.

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Amicrobial pustulosis of the folds is a chronic relapsing neutrophilic dermatosis characterized by sterile pustules compromising skin folds, scalp, face and periorificial regions. It predominantly affects women. Demodicosis is an inflammatory disease associated with cutaneous overpopulation of the mite Demodex spp., the pathogenesis of which is not completely established, but is frequently related to local immunodeficiency. A case of a young woman with amicrobial pustulosis of the folds, and isolated worsening of facial lesions, is reported; investigation revealed overlapping demodicosis. There was complete regression of lesions with acaricide and cyclin treatment. This case warns of a poorly diagnosed but disfiguring and stigmatizing disease, often associated with underlying dermatoses or inadvertent treatments on the face.

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Desafios no diagnóstico e tratamento de um caso de síndrome SAPHO na infância

Cited by 4 publications

References 6 publications

Pharmacological Management of Pediatric Pustular Psoriasis

Pharmacological Management of Pediatric Pustular Psoriasis

Spontaneous acne fulminans treated with corticotherapy, antibiotics and oral isotretinoine

Demodicosis as treatment complication of amicrobial pustulosis of the folds

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