Alergia ao látex em profissionais de saúde de São Paulo, Brasil

Montalvão, Leticia Nunes; Pires, Mário Cézar; Mello, João Ferreira de

doi:10.1590/s0365-05962008000300004

Cited by 3 publications

(4 citation statements)

References 23 publications

(23 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…9 Of the several antigens identified (Hev b1 to 13), Hev b2, Hev b4, Hev b5 and Hev b6 are especially important in health care workers. 14 Class 0 17 100 11 92 13 100 9 64 8 89 7 78 Class 1 ------3 21 1 11 1 11 Class 2 --1 8 --2 15 --1 11 Table 4: Classification of the serum samples of the individuals regarding specific IgE to natural latex from the rubber tree in their respective groups n = número de pacientes; C = grupo-controle de baixa exposição ao látex; C LX = grupo-controle de alta exposição ao látex; U BMV = grupo usuário BMV; U C = grupo ulcerado-controle; N = grupo caso novo allergy in 90% of the health care workers.…”

Section: Discussionmentioning

confidence: 99%

“…The ImmunoCAP test has satisfactory levels of detection of the following antigens: Hev b1, Hev b2, Hev b3, Hev b5, Hev b6, Hev b 6.01, Hev b 6.02 Hev b7.01, Hev b 7.02, Hev b8, Hev b10 and Hev b11 . 9 The various published studies show differences in terms of prevalence of latex allergy in health care workers using the same diagnostic method. 11,[18][19][20][21] It is known that the use of gloves without powder and of vinyl reduces the prevalence of latex hypersensitivity among health care workers.…”

Section: Discussionmentioning

confidence: 99%

“…Recently, there are numerous reports of type I or immediate hypersensitivity among professionals who deal with latex, directly related to the latex protein makeup. 9 Epidemiologically, some groups are reported to be at high-risk of developing hypersensitivity, such as individuals with spina bifida, health-care workers, workers at latex factories, and patients with history of allergy to fruit like avocado, banana, kiwi, chestnut and papaya. In addition to these groups, there are also atopic patients and/or patients with a family history of atopy and those with a history of multiple surgical procedures.…”

Section: Introductionmentioning

confidence: 99%

“…In addition to these groups, there are also atopic patients and/or patients with a family history of atopy and those with a history of multiple surgical procedures. 9,10 Since the natural latex extracted from Hevea brasiliensis is the main constituent of the natural biomembrane -which has been consolidated as an important adjuvant in the healing of various tissues, it becomes important to investigate hypersensitivity reactions among individuals with leg ulcers treated with the natural latex biomembrane in comparison with untreated ulcerated individuals and healthy professionals that belong to the group at risk of developing latex hypersensitivity.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Curativo de biomembrana vegetal e hipersensibilidade

Frade

Netto

Gomes

et al. 2011

An. Bras. Dermatol.

View full text Add to dashboard Cite

INVESTIGATIONAbstract: BACKGROUND: The natural biomembrane of latex extracted from Hevea brasiliensis has been used as a dressing for skin ulcers. OBJECTIVES: To evaluate how safe the natural biomembrane is in relation to hypersensitivity to latex when used as a dressing. METHODS: We selected patients with skin ulcers, forming the following groups: control -low occupational exposure to latex (n = 17); latex-exposed control -high occupational exposure (n = 14); ulcerated, using the natural biomembrane (n = 13); ulcerated control, not using the natural biomembrane (n = 14); and new cases (n = 9), assessed before and after 3 months of using the natural biomembrane. All patients underwent clinical and epidemiological evaluation for latex hypersensitivity and specific IgE (UniCap ® ), and the control and latex-exposed control groups underwent the patch test. RESULTS: Hypersensitivity was positive in 64.7% of the patients in the control group, 71.4% of the patients in the latex-exposed control group, 61.5% of the ulcerated using the natural biomembrane, 35.7% of the ulcerated control, and only 22 , 2% of the new cases. In the patch test of the control and latex-exposed control groups, only one individual in the control group (low contact) showed erythema in the first reading, which became negative in the second. The mean contact with latex in the latex-exposed control group was 3.42 hours / day. In the fluoroimmunoenzymatic assay, most of the sera was classified as zero (range 0-6). No serum was rated above 2, which is not considered significant for hypersensitivity (classification > 4). CONCLUSION: The natural biomembrane proved to be safe as a dressing, for it did not induce hypersensitivity reactions among the volunteers who underwent the patch test or among users of the natural biomembrane, as it was clinically and immunologically demonstrated by IgE levels. Keywords: Biological dressings; Latex hypersensitivity; Leg ulcer; Wound healing Resumo: FUNDAMENTOS: A biomembrana vegetal do látex da seringueira Hevea brasiliensis tem sido usada como curativo para úlceras cutâneas. OBJETIVOS: Avaliar a segurança da biomembrana vegetal como curativo em relação à hipersensibilidade ao látex. MÉTODOS: Foram selecionados pacientes com úlceras cutâneas constituindo-se os grupos: controle -baixa exposição profissional ao látex (n=17); alta exposição profissional (n=14); ulcerados em uso da biomembrana vegetal (n=13); ulcerados-controle sem uso da biomembrana vegetal (n=14) e casos novos (n=9), submetidos à avaliação pré e após 3 meses de uso da biomembrana vegetal. Todos foram submetidos à avaliação clínico-epidemiológica quanto à hipersensibilidade ao látex e IgE específica (UniCap ® ), e os grupos controle e controle exposto ao látex ao "patch test". RESULTADOS: A história de hipersensibilidade foi positiva em 64,7% dos pacientes do grupo-controle, 71,4% do controle exposto ao látex, 61,5% dos ulcerados em uso da biomembrana vegetal, 35,7% dos ulcerados-controle, e apenas 22,2% no grupo casos novos. Ao teste de contato dos gru...

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Curativo de biomembrana vegetal e hipersensibilidade

Frade

Netto

Gomes

et al. 2011

An. Bras. Dermatol.

View full text Add to dashboard Cite

show abstract

Sensibilidade ao Látex e Dosagem de Anticorpos Específicos em Profissionais da Área da Saúde

Gomes

Barbosa

Dias

et al. 2012

Ciênc. saúde coletiva

View full text Add to dashboard Cite

Resumo O objetivo deste estudo foi verificar a ocorrência da reação de sensibilidade ao látex e realizar dosagem de anticorpos antilátex em profissionais dos cursos de odontologia, medicina e enfermagem da Universidade Federal do Espírito Santo (UFES), Vitória-ES, Brasil. Estudo observacional, transversal. A amostra intencional foi composta por 295 profissionais. A sensibilidade foi avaliada por meio de questionário estruturado e validado, e a presença de IgE-látex por meio da coleta de 10ml de sangue submetido a análise com emprego do sistema Immunocap-Pharmacia®. Os valores IgE-látex foram distribuídos em diferentes classes. Resultados: 22,4,% (n=66) apresentaram sensibilidade ao látex, classe V IgE latex (17,6-42 KUA\L); 77,6 % (n=229) sem sensibilidade, classe 0 IgE-látex (<0,35KUA\L). O teste de Fisher mostrou correlação estatística significativa (p<0,05) em relação às seguintes variáveis: gênero; atopia; eczema nas mãos; alergia a medicamento; doença crônica; uso de anti-inflamató-rio; cirurgias anteriores. Conclusão: Observou-se valores positivos de IgE-látex nos profissionais com sensibilidade ao látex, sugerindo a necessidade de adoção de medidas profiláticas para a prevenção e ou adequação do ambiente de trabalho, preservando a saúde destes trabalhadores. Palavras-chave Saúde do trabalhador, Sensibilidade ao látex, Imunologia Abstract The scope of this study was to verify the occurrence of sensitivity to latex and conduct dosage of anti-latex antibodies in health professionals of the Dental, Medical and Nursing Schools of the Federal University of Espírito Santo (UFES), Vitoria, ES, Brazil. This was a cross-sectional observational study. The intentional sample was composed of 295 professionals. Sensitivity was evaluated by means of a structured and validated questionnaire and the presence of IgE-latex by means of collection of 10 ml of blood submitted to analysis using the Immunocap-pharmacia® system. The IgE-latex values were categorized in different groups. Results: 22.4% (n=66) showed latex sensitivity, class V of the IgE latex (17.5-42 KUA\L); 77.6 % (n=229) showed no sensitivity, class 0 or 1 of the IgE-latex (<0.35KUA\L-8,6KUA\L). Fisher's test showed a significant correlation statistic (p<0.05) in relation to the following variables: gender; atopy; eczema of the hands; allergy to medicination; chronic illness; use of anti-inflammatory; prior surgeries. Conclusion: Positive values of IgE were observed in the professionals with sensitivity, suggesting the adoption of prophylactic measures for the prevention and or adaptation of the work environment, preserving the health of these workers.

show abstract