Vitiligo: avaliação histológica e clínica após curetagem seqüencial

Barros, Jefferson Alfredo de; Filho, Carlos D'Aparecida Santos Machado; Martins, Lourdes Conceição; Pettinati, Juliana; Pinhal, Maria Aparecida da Silva

doi:10.1590/s0365-05962007000400005

Cited by 3 publications

(1 citation statement)

References 19 publications

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“…Por outro lado, mãos e pés mostraram repigmentação inferior a 25%, em todos os casos. Isso pode acontecer por serem áreas pobres em folículos pilosos locais, onde estão presentes os melanócitos inativos, que constituem reserva melanocítica não afetada pelo vitiligo e são importantes no processo de repigmentação, o que ocorre mediante a estimulação de imunocitocinas e mediadores in lamatórios que agem como "sinais" para migração de melanócitos a partir dos folículos pilosos da pele normal (28)(29)(30)(31)(32).…”

Section: Discussionunclassified

Efeitos da aplicação do L.A.S.E.R. HeNe e do ultravioleta B no vitiligo

Macedo

Oliveira²,

Silva³

et al. 2012

Fisioter. mov.

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Fisioter Mov. 2012 jul/set;25(3):481-8 ISSN 0103-5150 Fisioter. Mov., Curitiba, v. 25, n. 3, p. 481-488, jul./set. 2012 Licenciado sob uma Licença Creative Commons [T] Efeitos da aplicação do L.A.S.E.R. HeNe e do ultravioleta B no vitiligo foi de 4,43 cm² ± 5,17, com diferença média de 0,92 cm² ± 1,29. Conclusão: Ambos os aparelhos obtiveram resultados signi icativos na redução da mácula, com maior redução no grupo da ultravioleta. Application purposes of HeNe L.A.S.E.R. and ultraviolet B in vitiligo[P] [K] Palavras

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Section: Discussionunclassified

Efeitos da aplicação do L.A.S.E.R. HeNe e do ultravioleta B no vitiligo

Macedo

Oliveira²,

Silva³

et al. 2012

Fisioter. mov.

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Trichloroacetic Acid in Different Concentrations: A Promising Treatment Modality for Vitiligo

Nofal

Fawzy

Alakad

2020

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BACKGROUND Despite the recent advances in the treatment of vitiligo, results are still largely unsatisfactory and many patients show either weak or no response to treatment. Few clinical trials have investigated the use of trichloroacetic acid (TCA) to induce repigmentation in stable vitiligo. OBJECTIVE To evaluate the efficacy and safety of TCA, in different concentrations, for the treatment of stable localized vitiligo. METHODS The study included 100 patients with acral/nonacral stable vitiligo. Trichloroacetic acid was applied, as a monotherapy, to the vitiliginous patches at different concentrations according to the treated site every 2 weeks until complete repigmentation or for a maximum of 6 treatment sessions. Follow-up was done every month for 6 months to detect any recurrence. RESULTS Eyelid vitiligo showed the highest response to TCA treatment (excellent response in 80% of cases), followed by the face, trunk, and extremities. Lower response rates were noticed in the hands and feet vitiligo. Adverse effects were transient and insignificant in few patients. CONCLUSION Trichloroacetic acid seems to be a potential, cost-effective, well-tolerated therapeutic option for the treatment of vitiligo in the adults and pediatric populations.

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Action of topical mometasone on the pigmented halos of micrografting in patients with vitiligo

Saldanha

Filho

Paschoal

2012

An. Bras. Dermatol.

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BACKGROUND: Vitiligo is a prevalent skin pigmentation disorder worldwide. The treatments available still offer limited results to some patients. For patients with clinically stable vitiligo, melanocyte transplantation is an appropriate treatment option, and the technique of autologous punch grafting shows good repigmentation. OBJECTIVE: To evaluate the effect of topical mometasone on the halos of repigmentation after autologous punch grafting in patients with clinically stable vitiligo. METHODS: Between 2009 and 2010, 11 patients with clinically stable vitiligo (7 generalized, 2 focal and 2 segmental) underwent autologous punch grafting in the achromic patches. According to the clinical type of vitiligo, patients were instructed to use the corticosteroid ointment during 6 months, only on a few grafted lesions. In the first month, the mometasone ointment was used twice a day and after that just once. They were reassessed 1, 3 and 6 months after the procedure. Grafted halos were photographed and recorded using the software fotofinder. After 6 months, all the treated and untreated areas of the repigmentation halos were measured and analyzed comparatively. RESULTS: The median area of the repigmentation halos after 6 months of treatment with mometasone was larger (25,96 mm² ) than the one of the untreated halos (13,86 mm² ), showing a statistically significant difference (p = 0,026). CONCLUSION: In this study, the use of mometasone ointment increased the area of the repigmentation halos after punch grafting. However, this should be further investigated in larger samples in order to validate this positive action in the treatment of stable vitiligo.

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Vitiligo: avaliação histológica e clínica após curetagem seqüencial

Cited by 3 publications

References 19 publications

Efeitos da aplicação do L.A.S.E.R. HeNe e do ultravioleta B no vitiligo

Efeitos da aplicação do L.A.S.E.R. HeNe e do ultravioleta B no vitiligo

Trichloroacetic Acid in Different Concentrations: A Promising Treatment Modality for Vitiligo

Action of topical mometasone on the pigmented halos of micrografting in patients with vitiligo

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