1997 Abstract: very sensitive method for estimating the concentration of crotamine in a solution was developed. This method was based on the time required for the appearance of permanent hyperextension of the rear legs of mice as a function of the dose administered. This method can be used to determine toxin doses as low as 0.32 mg/kg
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AN in vivo METHOD FOR ESTIMATING THE CONCENTRATION OF CROTAMINE IN A SOLUTION
Abstract: very sensitive method for estimating the concentration of crotamine in a solution was developed. This method was based on the time required for the appearance of permanent hyperextension of the rear legs of mice as a function of the dose administered. This method can be used to determine toxin doses as low as 0.32 mg/kg
. Its high specificity for crotamine means that it can be used to measure toxin concentrations in the presence of other proteins and polypeptid…
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