The thyroid nodule is the presentation of various diseases of this gland. It is a very common clinical condition, particularly when employing sensitive methods of image. In this context, fine needle aspiration (FNA) is the main tool for differential diagnosis and the best value for money in the evaluation of nodular thyroid disease. This study aims to evaluate the profile of patients with thyroid nodules that are submitted to FNA. The sample consisted of 77 patients with thyroid nodule to be punctured. Data were collected for a period of 5 months in the Medical Center Sergipe Integrated (CEMISE), located in Aracaju / SE. The sample comprised 77 patients. Within the sample were 73 female patients (94.8%) and 4 men (5.2%), predominantly aged between 50 and 59 years. As the number of nodes, 57.1% of the patients (44 patients) had only one node to be punctured, while 42.9% (33 patients) had more than one. The majority (58.3%) of the nodules studied showed size = 1.0 cm. The familial history of thyroid disease was found in 42 patients (54.5%) and hypothyroidism personal history corresponded to 16.9% of the sample. The ultrasound examination showed 42 cases of thyroiditis. The results confirm the higher prevalence of thyroid nodules in the female population with advanced age. However, the finding of a greater number of nodes with small diameter puncture indication differs from existing literature.