2003
DOI: 10.1590/s0104-42302003000100029
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Hiperpigmentação cutânea em pacientes com insuficiência renal crônica em hemodiálise infectados pelo vírus da hepatite C

Abstract: RESUMO -OBJETIVO. A hiperpigmentação cutânea é comumente encontrada em pacientes portadores de insuficiência renal crônica (IRC), sendo também uma das manifestações mais evidentes da Porfiria Cutânea Tarda (PCT). Essa doença, que tem sido relatada em pacientes em hemodiálise (HD), tem como um dos fatores precipitantes a infecção pelo vírus da hepatite C (HCVportante desencadeador de um distúrbio do metabolismo das porfirinas que pode se expressar clinicamente por esse sintoma [5][6][7][8] . O objetivo deste es… Show more

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Cited by 12 publications
(2 citation statements)
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“…Although the patients in the two studies were different in terms of the cultural context, they are in agreement with each other in terms of achieving similar results (4). Similarly, the results of a study by Choi et al indicated an increase in hyperpigmentation in renal patients treated with hemodialysis, which is in agreement with the findings of the present study (15). However, Pico et al (9) showed that hyperpigmentation decreased with increasing dialysis duration, which is in contrast with the results of the current study.…”
Section: Discussionsupporting
confidence: 92%
“…Although the patients in the two studies were different in terms of the cultural context, they are in agreement with each other in terms of achieving similar results (4). Similarly, the results of a study by Choi et al indicated an increase in hyperpigmentation in renal patients treated with hemodialysis, which is in agreement with the findings of the present study (15). However, Pico et al (9) showed that hyperpigmentation decreased with increasing dialysis duration, which is in contrast with the results of the current study.…”
Section: Discussionsupporting
confidence: 92%
“…The diffuse hyperpigmentation was present in 22% of the patients. 28,10 Hyperpigmentation could be a result of the increased melanin concentration on the basal and superficial layers of the dermis. Such phenomenon would occur due to the accumulation of betamelanocyte-stimulating hormone (B-MSH) secondary to reduction of renal function.…”
Section: Dermatosis In Hemodialysis and Transplant Patientsmentioning
confidence: 99%