Heavy ion interactions from Coulomb barrier to few GeV/n: Boltzmann Master Equation theory and FLUKA code performances

Battistoni, G.; Cavinato, M.; Cerutti, F.; Clivio, A.; Fabrici, E.; Gadioli, E.; Erba, E. Gadioli; Garzelli, Maria Vittoria; Mairani, A.; Empl, A.; Pinsky, L.; Ballarini, F.; Ottolenghi, A.; Fassó, A.; Ferrari, A.; Ranft, J.; Sala, P.

doi:10.1590/s0103-97332004000500051

Cited by 4 publications

(1 citation statement)

References 5 publications

(9 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Both models have underwent major improvements recently (Böhlen et al 2014, Battistoni et al 2016, so that the transitions between them would result in both smooth and physically consistent energy distributions, as depicted in figure 2. These models' consistency are key in reproducing heavy ion's interactions with matter, ensuring the correct use of double differential cross sections for all particles emitted in transition to the evaporation's light fragments, residual nuclei formation and fragmentation (Battistoni et al 2004, Battistoni et al 2007.…”

Section: Methodsmentioning

confidence: 99%

Experimental validation of the FLUKA Monte Carlo code for dose and $\beta^+$ -emitter predictions of radioactive ion beams

Augusto

Mohammadi²,

Tashima³

et al. 2018

Phys. Med. Biol.

View full text Add to dashboard Cite

In the context of hadrontherapy, whilst ions are capable of effectively destroying radio resistant, deep seated tumors, their treatment localization must be well assessed to ensure the sparing of surrounding healthy tissue and treatment effectiveness. Thus, range verification techniques, such as online positron-emission-tomography (PET) imaging, hold great potential in clinical practice, providing information on the in vivo beam range and consequent tumor targeting. Furthermore, emitting radioactive ions can be an asset in online PET imaging, depending on their half-life, compared to their stable counterparts. It is expected that using these radioactive ions the signal obtained by a PET apparatus during beam delivery will be greatly increased, and exhibit a better correlation to the Bragg Peak. To this end, FLUKA Monte Carlo particle transport and interaction code was used to evaluate, in terms of annihilation events at rest and dose, the figure of merit in using emitter, radioactive ion beams (RI). For this purpose, the simulation results were compared with experimental data obtained with an openPET prototype in various online PET acquisitions at the Heavy Ion Medical Accelerator in Chiba (HIMAC), in collaboration with colleagues from the National Institute of Radiological Sciences’ (NIRS) Imaging Physics Team. The dosimetry performance evaluation with FLUKA benefits from its recent developments in fragmentation production models. The present work estimated that irradiations with RI, produced via projectile fragmentation and their signal acquisition with state-of-the-art PET scanner, lead to nearly a factor of two more accurate definition of the signals’ peak position. In addition to its more advantageous distribution shape, it was observed at least an order magnitude higher signal acquired from 11C and 15O irradiations, with respect to their stable counterparts.

show abstract