Quality of colostral passive immunity and pattern of serum protein fluctuation in newborn calves

Abstract

Immunity acquired by newborn animals is known as passive immunity, and for ruminants, antibody acquisition depends on the ingestion and absorption of adequate amounts of immunoglobulins from colostrum. This study relates different initial levels of acquired passive protection and serum total protein (TP) and immunoglobulin G (IgG). Serum immunoglobulin concentration and total protein were evaluated for female Holstein calves in the first sixty days of life. Animals were separated into three groups according to their initial level of passive immunity: group 1-animals with a low level of passive immunity (below 20 mg mL -1 ); group 2-animals with a medium level (between 20 and 30 mg mL -1 ), and group 3-animals with a high level (above 30 mg mL -1 ). Serum total protein was determined through the biuret method and IgG was determined by radial immunodiffusion. Data were analyzed as a completely randomized, split-plot statistical design. Fluctuation of the variables along the experimental period was determined through non-linear regression by the DUD method (PROC NLIN -Non Linear SAS). Animals with low antibody acquisition started to produce antibodies earlier, reflecting a compensatory synthesis. On the other hand, animals having adequate levels exhibited an extended period of immunoglobulin catabolism and the beginning of the endogenous phase was delayed. Regardless initial levels, the fluctuations in IgG contents occurred around adequate physiological concentrations, ranging from 20 to 25 mg mL -1 .

Perfil bioquímico sérico de bezerros senepol nos primeiros 120 dias de idade

“…Os valores encontrados de proteínas totais nos primeiros 15 dias de vida são reflexo da concentração sérica de globulinas (4,44 ± 0,73 g/dL). Estes valores de globulinas devem-se, provavelmente, à absorção adequada de imunoglobulinas através da ingestão do colostro, a qual foi assistida em todos os animais, e posteriormente, devido à atividade catabólica e síntese endógena de imunoglobulinas (PAULETTI et al, 2003). Estes valores estiveram maiores que o descrito por pesquisadores brasileiros (COSTA et al, 2008), em bezerros da raça Nelore e Limousin, entre 24 e 36 horas, de 7,19 ± 0,75 g/ dl e 6,32 ± 0,98 g/dl, respectivamente, e Rocha et al (2010), em bezerros Canchim-Nelore, aos 7 e 15 dias, filhos de vacas primíparas (7,0 ± 0,35; 7,0 ± 0,16 g/dl) e pluríparas (6,71 ± 0,07; 7,4 ± 0,22 g/dl), respectivamente.…”

Transferência de imunidade passiva e proteinograma sérico em bezerros das raças Crioula Lageana variedade Mocha e Aberdeen Angus (Red Angus) nos primeiros seis meses de vida

“…De forma geral, após o pico de concentração sérica às 24 horas de vida, observa-se redução progressiva até os 30 ou 45 dias de idade, quando se estabelece uma nova curva ascendente, que se deve à síntese ativa de anticorpos pelo sistema imunológico competente (Ribeiro et al 1983, Moraes et al 1997, Fagliari et al 1998, Feitosa 1998, Costa 2000, Pauletti et al 2003. Exames laboratoriais têm sido desenvolvidos para a determinação direta e/ou indireta da transferência de imunidade passiva (TIP), uma vez que os índices de mortalidade e um menor desempenho produtivo estão relacionados à FTIP (Feitosa et al 2001b).…”

Serum Urea, Creatinine and Enzymatic Activity of Alkaline Phosphatase in Nelore Cattle Raised in the Micro Upper Middle Gurguéia

“…There is no expressivity, in number, in the literature national about subject and, the same way, international most investigations focuses in dairy cattle [7,8,9,10]. Few experiments have been developed for evaluation of animals to slaughter [11,12].…”