“…Swimming in circles, uncoordinated movements, and dorsal rigidness are indicators of the compromising of central nervous system. Salvador et al (2005) observed a high morbidity and mortality in S. agalactiae when tilapia were cultivated in net-tanks, which presented erratic and circular swimming, appetite decrease, uni-or bilateral exophthalmia and visceral cavity distension as main clinical signs. Main macroscopical alterations reported by Salvador et al (2003) were injuries in the skin, fins, branchiae, opacity of the cornea, liquid in visceral cavity, liver and splenomegaly.…”