Fatores de virulência presentes em amostras de Escherichia coli uropatogênicas - UPEC para suínos

Abstract

As infecções urinárias são freqüentes nos rebanhos suínos, sendo a principal causa de descarte e mortalidade de animais adultos. Apesar das características multifatoriais da doença o microrganismo freqüentemente isolado é a Escherichia coli. Vários fatores de virulência de Escherichia coli foram descritos em amostras uropatogênicas e permitem diferenciar cepas patogênicas de não patogênicas. Esta revisão tem por objetivo apresentar alguns tópicos relativos aos fatores de virulência presentes em amostras de E. coli uropatogênicas para suínos.

Virulence factors and antimicrobial resistance of escherichia coli isolated from urinary tract of swine in southern of Brazil

“…The more frequent patterns of resistance were to beta lactam, lincomicin, tetraciclyne, quinolone, macrolide, aminoglycoside and polymixin groups (data not shown). Plasmids and other genetic elements, like integrons, may be encountered in UPEC and are associated to coding virulence factors and MDR (4,5,18). In our study plasmids were found in 39.02% (32/82) of E. coli isolates.…”

“…The antibiotic therapy may select resistant bacteria (5,22). The resistance to antimicrobial drugs may be carried by plasmids, as well as chromosomal mutations that occur spontaneously (9).…”

In vitro inhibition of adhesion of Escherichia coli strains by Xylitol

“…For the EPEC strain, there were no cells in the positive control -mannose ( Figure 2C). One possible explanation for this in vitro study could be based on the fact that the EPEC strains had, among other adherence factors, fimbriae type 1 or mannose-sensitive (Brito et al, 2004). Therefore, when mannose was present in the medium, the adherence of bacteria to the slides was obstructed.…”

“…The bacterial fimbriae recognize some soluble carbohydrates that lead to adhesion blockage, in vitro, of some bacteria (Sharon and Ofek, 2000;Sharon, 2006). The presence of this type of fimbriae is common in the samples of E. coli from urinary and faecal origin (Girón, 1993;Brito et al, 2004). The effects of some compounds on the adherence of microorganisms are recent and there are few studies in the literature addressing this application (Ofek and Sharon, 2000).…”

Physical, chemical and biological aspects of the urine of sows in a certificated swine reproduction farm in the city of Toledo, Paran, Brazil

“…The impact of swine production on the global economy, especially in Brazil, which has the 3 rd largest herd of swine, and the State of Paraná as the 4th largest Brazilian producer of swine, has made it essential to have rigorous control of diseases affecting the economic yield and productivity of the heard, such as urinary infection (Dalla- Costa and Sobestiansky, 1999). Urinary tract infections cause great economic losses due to puerperal diseases, post-weaning infertility, expenses with medications, reduction of weight gain in piglets and mortality rates (Brito et al, 2004). Urinary problems are responsible for 50% of sudden death of sows in production and are the main cause of mortality among adult animals (Perestrelo and Perestrelo, 1988).…”