Oral tumors in dogs: clinical aspects, exfoliative cytology and histopathology

Abstract

In order to establish the diagnosis and prognosis of tumors of the oral cavity, a comparative study was carried out in 130 dogs considering age, sex, breed, clinical aspects, exfoliative cytology as well as histopathology. Exfoliative cytology revealed: 100% negative for benign non-odontogenic tumors, 97.91% negative benign odontogenic tumors and 77.92% positive for malignant tumors. Histopathology showed: 59.23% malignant tumors (33.08% malignant melanoma, 9.23% squamous cell carcinoma, 5.38% osteosarcoma, 2.31% fibrosarcoma, 2.31% angiosarcoma, 1.54% malignant mesenchymal tumors, 1.54% malignant fibrohistiocytoma, 1.54% lymphoma, 0.77% leyomyosarcoma, 0.77%% epithelioid sarcoma and 0.77% angiofibrosarcoma); 36.92% benign odontogenic tumors (25.38% peripheral odontogenic fibroma, 10.0% ossifyng fibroma and 1.54% odontoma) in addition to 3.85% benign non-odontogenic tumors (1.54% fibroma, 0.77% plasmocytoma, 0.77% pilomatrixoma and 0.77% giant tumor cells). These results permit us to conclude that exfoliative cytology was an efficient, safe, quick and noninvasive method and could be used for early evaluation of oral cancer.

Cytological Aspects of Equine Oral Fibrosarcoma

“…Furthermore [5], investigating oral tumors in dogs through exfoliative cytology and histopathology, found 100% agreement between both techniques to fibrosarcoma, which was considered a good result. Nevertheless, the authors considered a low number of sampling studied, since this is also a rare neoplasm in the oral cavity of dogs.…”

“…The imaging findings were consistent with the disease presented by the animal. Radiographic examination presented the local bone lysis and excluded the existence of advanced metastasis [5]. Thus, FNAC, in addition to the other complementary tests, enabled a better understanding of the evolution of the disease in the horse and assisted in its prognosis.…”

CT features of malignant and benign oral tumors in 28 dogs

“…4,6 Peripheral odontogenic fibromas are classified as hamartomas; which can grow large and produce bony proliferations, but are not aggressive enough to induce bone lysis. 3,12 Besides the epulis type, various benign tumors also develop in the oral cavity. 3,13 In general, oral tumors are resected surgically.…”

Análise da casuística das afecções cirúrgicas observadas, segundo o aparelho corpóreo analisado, no período de 1988 a 2007 na Clínica Cirúrgica de pequenos animais da Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo

“…De acordo com Felizzola et al (1997), há uma tendência de crescimento no número de neoplasias bucais em cães e gatos, embora tumores de boca benignos e malignos são freqüentes em cães e menos observados em gatos . A citologia esfoliativa se presta a detectar melanomas em cães (FELIZZOLA et al, 1999). Felizzola et al (2002) propõem técnicas operatórias modificadas àquela preconizada por Withrow e Holmberg (1983) para tratamento cirúrgico das neoplasias malignas de boca em cães, obtendo bons resultados no que tange ao retorno e na função da mastigação.…”

“…Bellei et al (2006) revelaram valores semelhantes, quando realizaram um estudo retrospectivo da prevalência de neoplasias cutâneas em 10.935 diagnósticos histopatológicos de cães. Aliado a isso, Queiroz (2004) diagnosticou e submeteu a tratamento cirúrgico segundo os grupos estudados, de acordo com o que se observa na literatura com os trabalhos de Stopiglia et al (1992) e Felizzola et al (1997Felizzola et al ( , 1999Felizzola et al ( , 2002 Novos estudos à semelhança da pesquisa levada a termo no presente momento devem ser empreendidos, enfocando, especificamente, as afecções, uma a uma de cada um dos sistemas e aparelhos abordados e a percentagem destas no universo da população canina e felina da Grande São Paulo, ou por 100.000…”