Objective: To identify and characterize socioeconomic inequalities in professionally administered topical fluoride treatment to schoolchildren. Methods: One thousand six hundred and forty-four schoolchildren [6 to 13 years of age, mean 9.06 ± 2.02; years 50.9% boys] were included in a cross-sectional study. Using questionnaires directed to mothers/guardians, we collected sociodemographic, socioeconomic and dental variables. The dependent variable was at least one professional application of topical fluoride by a dentist in the previous year. Dentists in Mexico carry out the scope of clinical care traditionally assigned to dental hygienists in the United States of America (USA) and Canada. A multivariate logistic regression model was generated. Results: The prevalence of fluoride application was 11.5 % (95% CI = 9.9, 13.0). In the multivariate model, the odds of having a topical fluoride application was higher in children who reported brushing teeth more often (