Mandibular periosteal (juxtacortical) chondrosarcoma

Costa, Elisângela Maria Cunha; Lucas, Bárbara Lima; Silva, Mariana Reis; Vilarinho, Renata Hinhug; Faria, Paulo Rogério de; Loyola, Adriano Mota

doi:10.1590/s0103-64402009000500013

Cited by 6 publications

(6 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A PubMed search of the English‐language literature for ‘periosteal chondrosarcoma’ and ‘juxtacortical chondrosarcoma’ resulted in available full‐text articles with, in total, 109 cases from 1955 until 2013, including a few small series containing up to 24 cases and case reports . Using the archives of the NCBT, we collected a relatively large series of 38 periosteal chondrosarcomas, for which clinicoradiological features have been described elsewhere by others .…”

Section: Discussionmentioning

confidence: 99%

Periosteal chondrosarcoma: a histopathological and molecular analysis of a rare chondrosarcoma subtype

et al. 2015

View full text Add to dashboard Cite

We report the first large histological and molecular study on periosteal chondrosarcoma showing that histopathological examination and molecular aberrations do not predict prognosis. Although the mutation frequency of IDH1 was low, we confirm the supposed relationship with central chondrosarcoma. Moreover, we identify loss of canonical Wnt signalling and deregulation of pRb signalling as possible events contributing to its histogenesis.

show abstract

Section: Discussionmentioning

confidence: 99%

Periosteal chondrosarcoma: a histopathological and molecular analysis of a rare chondrosarcoma subtype

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Similarly, histopathologic differentiation of JCS from CCS requires astute microscopic examination due to several common features [15]. In both instances, lobules of hyaline cartilage with irregular distribution of cells are present with tumor cells often exhibiting nuclear pleomorphisms.…”

Section: Discussionmentioning

confidence: 99%

“…In both instances, lobules of hyaline cartilage with irregular distribution of cells are present with tumor cells often exhibiting nuclear pleomorphisms. Calcification within the hyaline matrix and cortical invasion are also common findings, but no malignant osteoid or bone are present within the tumor [10,15]. Both CCS and JCS may reveal a fibrous peripheral capsule with projecting septa that delve into the tumor, partitioning the cartilage into variable-sized lobules.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Head and Neck Juxtacortical Chondrosarcoma: A Systematic Review

Jones¹,

Alwani²,

Summerlin³

et al. 2019

AOHNS

View full text Add to dashboard Cite

Objective: To present a case and systematically evaluate trends in clinical presentation, imaging, histopathology, and management modalities and outcomes of all head and neck juxtacortical chondrosarcoma (HNJCS) cases reported in the existing literature. Methods: We describe a rare case of HNJCS from our tertiary referral center following which the PubMed, MEDLINE, Embase, and Web of Science databases were searched for all HNJCS reports. Relevant titles and abstracts were screened. Resulting full-text articles were assessed for eligibility, and remaining studies were included for data extraction, summarization, and analysis. Results: Potential studies were identified dating from May 1946 to February 2019. A total of nine cases were included in our systematic review, eight of which were identified from full-text articles and one recruited from our tertiary referral center. The median presentation age was 41 years with a 66.7% male preponderance. The commonest presenting sign was a painless, isolated swelling after a median symptom duration of 2.5 months. CT imaging revealed hypodense lesions with peripheral enhancement and micro-calcifications. T1-weighted MRI showed hypo-to iso-intense, lobulated masses with peripheral and/or septal enhancement. The masses were diffusely hyper-intense on T2-weighted MRI. Histopathology demonstrated septated lobules of malignant hyaline cartilage with a peripheral fibrous capsule. Most tumors were low-or intermediate-grade tumors with average diameter of 4.3 cm. Local recurrence was identified in only one case (four years after initial resection). No distal and/or nodal metastases were identified. All tumors were managed by wide-or narrow-margin surgical excision. Two reports employed adjuvant treatment. There was no evidence of disease at final follow-up (median of 1.5 years). Conclusion: To the best of our knowledge, only nine cases of HNJCS have been adequately described. HNJCS have relatively consistent clinical and diagnostic profile regardless of location in the body. Surgical management yields excellent outcomes with low recurrence rates.

show abstract

“…In the maxillofacial region, only a few cases of juxtacortical chondrosarcoma affecting the mandible, other than the symphysis region, have been reported so far. [ 4 5 ]…”

Section: Introductionmentioning

confidence: 99%

Marginal resection in a case of juxtacortical chondrosarcoma of the mandible

Panchanathan

Kamalakaran

Duraisamy

et al. 2018

Natl J Maxillofac Surg

View full text Add to dashboard Cite

Chondrosarcomas usually invite extensive surgical resection. These are malignant tumors of cartilaginous origin and their involvement in the maxillofacial region is rare. Juxtacortical chondrosarcoma, a distinct malignant cartilage-forming tumor arising from the external surface of a bone, is extremely rare in the mandible. Here, one such case with a relatively good prognosis is presented where marginal resection as a surgical option yielded good result.

show abstract

Mandibular periosteal (juxtacortical) chondrosarcoma

Cited by 6 publications

References 13 publications

Periosteal chondrosarcoma: a histopathological and molecular analysis of a rare chondrosarcoma subtype

Periosteal chondrosarcoma: a histopathological and molecular analysis of a rare chondrosarcoma subtype

Head and Neck Juxtacortical Chondrosarcoma: A Systematic Review

Marginal resection in a case of juxtacortical chondrosarcoma of the mandible

Contact Info

Product

Resources

About