Periradicular repair after two-visit endodontic treatment using two different intracanal medications compared to single-visit endodontic treatment

Abstract

The number of appointments necessary to treat infected root canals is one of the most controversial issues in endodontics. This study evaluated, in dogs, the response of the periradicular tissues to the endodontic treatment of infected root canals performed in a single visit or in two visits, using different interappointment dressings. Periradicular lesions were induced by inoculating Enterococcus faecalis in the root canals. After confirming that a periradicular lesion developed, the root canals were treated within one or two visits, using either ozonized oil or calcium hydroxide in camphorated paramonochlorophenol (CMCP) as an intracanal medication. After 6 months, the animals were sacrificed and the specimens were processed for histological and histobacteriological analysis. The root canals treated in a single visit showed a success rate of 46%. When a calcium hydroxide/CMCP-based interappointment intracanal medication was used, 74% of the cases were categorized as success. In cases where ozonized oil was used as the intracanal medication, a success rate of 77% was observed. These results of the present study demonstrated that the two-visit treatment offered a higher success rate compared to one-visit therapy. In addition, ozonized oil may potentially be used as an intracanal medication.

Influence of serum and necrotic soft tissue on the antimicrobial effects of intracanal medicaments

“…This combination has already been demonstrated to exhibit pronounced antibacterial activity against several candidate endodontic pathogens (13,14,16). Although CPMC exhibits high toxicity when used alone, satisfactory biocompatibility results have been observed for its association with CH in animal studies (17,18). Clinical studies evaluating the incidence of postoperative pain (19), antibacterial activity (3) and treatment outcome (20) have demonstrated excellent results when using an antibacterial protocol for treatment that includes a 7-day interappointment medication with CHPG.…”

Antimicrobial Effectiveness of Intracanal Ozone Treatment

“…It is known that higher concentrations of NaOCl possess a greater irritation effect on the apical cells and periapical tissues (38). Silveira et al have shown that 2.5% NaOCl solution and 2% chlorhexidine completely remove bacterial infection of E. faecalis after 30 s of contact (39).…”

Effectiveness of gutta-percha and Resilon in filling lateral root canals using the Obtura II system

“…4,5 The filling technique and the properties of the material employed are the two essential factors for three-dimensional filling of the root canal system. [6][7][8] It has been suggested that the ideal root canal filling should consist of a sufficient amount of gutta-percha covered by a thin layer of a sealer.…”

“…One of these devices was the Obtura II system, which heats and injects the plasticized gutta-percha into the canal 5 . Karr et al 21 and Karabucak et al 22 observed that both Resilon and Obtura gutta-percha showed similar results when lateral grooves and dentin depressions were filled using the Obtura II system.…”