Comparative study of MTA and other materials in retrofilling of pulpless dogs' teeth

Abstract

This in vivo study compared the effect of mineral trioxide aggregate (MTA), IRM, Super EBA and ZOE in a puttylike consistency, used as retrofilling materials, in the healing process of periapical tissue of pulpless dogs' teeth submitted to a conventional retrofilling technique. Twenty-four premolars obtained from three dogs were used. At the first intervention, the animals were anesthetized, coronal access was obtained and pulpectomy was done. Root canals were kept open to the oral environment for 180 days to induce the formation of apical lesions. After surgical removal of the lesions with curettes, 2 mm of the apical root was cut out perpendicular to the long axis of the teeth, and root-end cavities were shaped with a low-speed round bur. The bone cavities were irrigated and dried, and the root-end cavities were filled with MTA, IRM, Super EBA and ZOE in a puttylike consistency. The bone cavities were passively filled with blood and flaps were sutured. The coronal access openings were cleaned and double-sealed with ZOE and amalgam. After 180 days, the animals were killed by anesthetic overdose, maxilla and mandible were removed and the pieces were processed for histomorphologic analysis. Data were evaluated blindly on the basis of several histopathologic events and the scores obtained were analyzed statistically using the Kruskal Wallis test. No significant differences were observed among MTA, Super EBA and IRM (p>0.05). However, ZOE had a significantly more negative influence on the apical healing (p<0.05). In conclusion, MTA, Super EBA and IRM had similar histopathologic effects among each other and better performance than ZOE used in a puttylike consistency. Furthermore, only MTA stimulated hard tissue deposition in direct contact with the retrofilling material, even when it was inserted under critical conditions.

In vitro antimicrobial activity of endodontic sealers, MTA-based cements and Portland cement

“…The root canal sealers were manipulated as recommended for use as root-end filling materials. Accordingly, Sealer 26 was used as proposed by Tanomaru-Filho et al (7), zinc oxide and eugenol cement according to Bernabé et al (19), and Sealapex with zinc oxide was mixed using the proportions recommended by Tanomaru-Filho et al (7). Portland cement and MTA-based materials were manipulated in accordance with the manufacturer's instructions.…”

Apical barrier technique using MTA: report of two cases

“…Calcium hydroxide has been extensively used to accomplish apical closure due to its ability to induce hard tissue formation, but it is more time consuming. (4,5) .MTA was used in immature premolars of dogs and was concluded that it induced apical plug more often with less inflammation. (6) MTA has shown good sealing abilities and biocompatibility to the periradicular tissue.…”

Apexificação com hidróxido de cálcio ou agregado trióxido mineral: revisão sistemática

“…Apexificação ou apicificação é o processo de formação de barreira apical calcificada ou de promoção do desenvolvimento continuado da raiz que apresenta rizogênese incompleta e polpa necrosada, mediado por uma técnica terapêutica aplicada [8][9][10][11] . Assim, busca-se construir um ambiente aceitável para obturação de forma convencional, sem que haja o extravasamento de material para região apical 1,8 .…”

“…Assim, busca-se construir um ambiente aceitável para obturação de forma convencional, sem que haja o extravasamento de material para região apical 1,8 . O sucesso da apexificação está relacionado ao diagnóstico preciso, ao conhecimento dos processos biológicos e, principalmente, dos materiais utilizados, com o objetivo de promover a deposição de tecido mineral no ápice dental 9,10 . O medicamento mais comumente utilizado para promover apexificação na raiz de um dente é o Hidróxido de Cálcio, em virtude da sua alcalinidade (pH 12,8), das excelentes propriedades bacteriológicas e da indução mineralizadora 6,7,11 .…”

“…O medicamento mais comumente utilizado para promover apexificação na raiz de um dente é o Hidróxido de Cálcio, em virtude da sua alcalinidade (pH 12,8), das excelentes propriedades bacteriológicas e da indução mineralizadora 6,7,11 . Recentemente, considerável interesse tem sido expresso no uso de MTA (Mineral Trioxide Aggregate ou Agregado Trióxido Mineral) (Universidade de Loma Linda, Califórnia, Estados Unidos) no tratamento de retro-obturações, trepanações acidentais, reabsorções internas com perfuração, apexificação, capeamento pulpar e pulpotomia 10,12 . O MTA, quando em contato com fluídos teciduais, promove liberação de hidróxido de cálcio 12,13 , o que faz deste cimento um material altamente alcalino (pH 12,5), conduzindo ação antimicrobiana e capacidade mineralizadora 11 , indução de cementoblastos e osteoblastos 14,15 , e também promoção de um excelente selamento marginal 9,16 .…”