Anemia e transfusões de concentrados de hemácias em pacientes graves nas UTI brasileiras (pelo FUNDO-AMIB)

Abstract

JUSTIFICATIVA E OBJETIVOS: A anemia é uma condição comum em pacientes graves. A transfusão de hemoderivados aumenta de forma significativa o risco de transmissão de agentes infecciosos e afeta o perfil imunológico. O objetivo deste estudo foi avaliar a incidência de anemia e a prática de transfusão de hemá

Transfusão de concentrado de hemácias na unidade de terapia intensiva

“…(6,17) In the study by Hebert et al, it was seen a prevalence of the male gender, 64%, similar to the observed in the Eastern Europe study. (10,17) In the HNSC ICU the prevalence found was 56.05%, very close to the observed by Chohan et al, 58%, as well as in the Brazilian multicenter study by Lobo et al (5,22) However, the studies did not show a gender influence on pretransfusion parameters, nevertheless the populations differences. (6,10,18) There is an association between the ICU stay and packed red cells transfusion; the longer is the ICU stay, the higher is the transfusion rate.…”

“…(10,14,18) These rates are similar to other studies conducted in Brazil, 35%. (21,22) The transfusion rate for the patients in the HNSC study was 19,33%. Significant differences found in the transfusion rates may be explained by the patients population profile within a given hospital, as well as by the recommended treatments and possible complications.…”

“…(17,18) In the HNSC ICU there was a predominance of patients aged 60 years or older, and this feature is repeated in Brazilian ICUs. (21,22) This predominance of older patients coincides with a lager number of comorbidities and hospital stay. (6,17) In the study by Hebert et al, it was seen a prevalence of the male gender, 64%, similar to the observed in the Eastern Europe study.…”

“…This is repeated in other Brazilian trials, both the multicenter and the one by the HUCFF, where the mean ICU stay was 6 days. (21,22) Hebert et al found a 39% incidence of packed red blood cells transfused patients coming from the surgery center, and 16% from the emergency. (10) In the Eastern Europe 57.5% of the patients admitted due to emergency surgery were transfused.…”

“…In the Brazilian studies, more than 50% of the transfusion indications are related to the hemoglobin level, with no relationship to active bleeding. (21,22) The number of red blood cells transfused units ranged between 2.6-4.1 units/patient in an ICU multicenter study. (10) In Scotland it was found that the ICU surviving patients used an average 2.3 units per TE of this blood component.…”