Dihydropyranoflavones from Pongamia pinnata

Abstract

²,4 -dihydro- 3 -hydroxy-4 -acetoxy)-2 ,2 -dimethylpyrano-(7,8:5 ,6 )-flavone and 3-methoxy-(3 ,4 -dihydro-4 - hydroxy-3 -acetoxy)-2 ,2 -dimethylpyrano-(7,8:5 ,6 )-flavone, were isolated, along with six known compounds, caryophyllene oxide, obovatachalcone, 8-hydroxy-6-methoxy-3-pentyl-1H-isochromen-1-one, 6,7,2,2-dimethylchromono-8,gamma,gamma-dimethylallylflavanon e, isolonchocarpin, ovaliflavanone A. Their structures were determined on the basis of the spectroscopic data interpretation.]]>

Effects of Ethanolic Extract of the Leaves of Pongamia glabra and Gliricidia sepium against Rhipicephalus (Boophilus) annulatus

“…Phytoconstituents of P. glabra include furanoflavonols, chromenoflavones, flavones, furanodiketones and flavonoid glucosides (Pathak et al, 1983;Ahemed et al, 2004;Yin et al, 2006). Karanjin, β-sitosterol, pongamol, pongaglabrone, pongapin, kangone, glabrachromene, pongaflavone, pongol, glabrachrome-II and glabrachalcone were previously isolated from seeds of P. glabra.…”

8‐Prenylflavanones through Microwave Promoted Tandem Claisen Rearrangement/6‐endo‐trig Cyclization and Cross Metathesis

“…The same natural product was later isolated from the stem bark of the tree Pongamia pinnata , a medicinal plant found in Southeast Asia and Australia. [ 55,56 ] Although 8 has only one actual prenyl substituent it is nevertheless a double prenylated flavonoid, because the chromene part is biosynthetically derived from an ortho ‐prenyl phenol through a cyclase catalyzed cyclization. [ 57,58 ]…”

“…The same natural product was later isolated from the stem bark of the tree Pongamia pinnata, a medicinal plant found in Southeast Asia and Australia. [55,56] Although 8 has only one actual prenyl substituent it is nevertheless a double prenylated flavonoid, because the chromene part is biosynthetically derived from an ortho-prenyl phenol through a cyclase catalyzed cyclization. [57,58] For the chemical synthesis of chromenes we [59] and others [60] have used a microwave promoted propargyl-Claisen rearrangement, a transformation that starts from propargyl ethers and proceeds through allene intermediates.…”

Antihyperglycemic Activity ofPongamia pinnataStem Bark in Diabetic Mice

“…Preliminary phytochemical analysis of the stem bark of Pongamia pinnata showed presence of alkaloids, glycosides, phenolic compounds, flavonoids, furanoflavones, chromenoflavones, flavonodiaketones, pongaflavonol, pyranochalcones, and flavonoid glycoside (Krishna & Grampurohit, 2006;Yin et al, 2006aYin et al, , 2006bYin et al, , 2005Carcache-Blanco et al, 2003;Asalkar et al, 2000;Tanaka et al, 1992;Pathak et al, 1983;Talapatra et al, 1982). The antihyperglycemic activity of PPSBAE may be due to the presence of several bioactive antidiabetic principles.…”