2008
DOI: 10.1080/13880200802370381
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Antihyperglycemic Activity ofPongamia pinnataStem Bark in Diabetic Mice

Abstract: Pongamia pinnata (L.) Pierre (Fabaceae), popularly known as "Karanj" or "Karanja" in Hindi, and Indian beech in English, is a medium-sized glabrous tree. In the present study we report the antihyperglycemic activity of stem bark of alcohol extract of Pongamia pinnata (PPSBAE). Based on acute oral toxicity data, PPSBAE showed no mortality in normal mice up to 5,000 mg/kg. PPSBAE was administered as three doses (i.e., 100, 200, and 400 mg/kg) to diabetic mice, and the serum glucose level and body weight were mea… Show more

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Cited by 14 publications
(6 citation statements)
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“…Pongamia pinnata (Fabaceae) is popularly known as Indian beech in English [4]. Commonly known by its vernacularnames karanj (Hindi), honge/karajata (Kannada), pungai (Tamil).…”
Section: Introductionmentioning
confidence: 99%
“…Pongamia pinnata (Fabaceae) is popularly known as Indian beech in English [4]. Commonly known by its vernacularnames karanj (Hindi), honge/karajata (Kannada), pungai (Tamil).…”
Section: Introductionmentioning
confidence: 99%
“…Commonly known by its vernacularnames karanj (Hindi), honge/karajata (Kannada), pungai (Tamil). As per the literature the extract of stem bark of P. pinnata (L.) showed antihyperglycaemic activity in diabetic mice [18]. Further, reports available that concomitant administration of synthetic oral hypoglycemic drugs along with P. pinnata produced synergistic effect in diabetic mice [19].…”
Section: Introductionmentioning
confidence: 90%
“…Commonly known by its vernacularnames karanj (Hindi), honge/karajata (Kannada), pungai (Tamil). As per the literature the extract of stem bark of P. pinnata (L.) showed antihyperglycaemic activity in diabetic mice [9]. Further, reports available that concomitant administration of synthetic oral hypoglycemic drugs along with P. pinnata produced synergistic effect in diabetic mice [10].…”
Section: Introductionmentioning
confidence: 90%