volume 24, issue 3, P388-392 2011
DOI: 10.1590/s0103-21002011000300013
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Abstract: ABSTRACTObjective: To investigate the renoprotective effects of the extract of Vitis vinifera L in the Tacrolimus-induced nephrotoxicity in experimental studies with rats. Methods: Quantitative survey with an experimental model in which adult male, Wistar rats, weighing between 250g -300g, were used. The rats were treated once a day for cincodias by gavage as follows: Saline (control, sodium chloride, 0.1 ml); Vitis (Vitis vinifera L 3mg/kg), FK (0.5 mg / kg); and, FK + Vitis (0.5 mg / kg + 3 mg / kg, respect…

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