Pulmonary function of children with acute leukemia in maintenance phase of chemotherapy

Macêdo, Thalita Medeiros Fernandes de; Campos, Tânia; Mendes, Raquel Emanuele de França; França, Danielle C.; Chaves, Gabriela; Mendonça, Karla Morganna Pereira Pinto de

doi:10.1590/s0103-05822014000400007

Cited by 2 publications

(2 citation statements)

References 18 publications

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“…In the present study, leukemia was the most related to respiratory distress syndrome type of cancer, agreeing with Pillon et al (2019), who found the same type of cancer in 59% of PICU admissions, probably because it is the most prevalent one in childhood (Macêdo et al, 2014).…”

Section: Discussionsupporting

confidence: 91%

Risk factors in acute respiratory distress syndrome among children with cancer in Brazilian Amazon: An observational study

Farias¹,

Júnior²,

Dias³

et al. 2021

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This study was undertaken to determine the incidence and potential risk factors associated with Acute Respiratory Distress Syndrome (ARDS) in pediatric oncologic patients undergoing invasive mechanical ventilation and the association between mortality risk factors and ARDS. Retrospective cohort study was conducted using data analysis of patients on admission to the PICU, that were submitted to invasive mechanical ventilation for over 24 hours. Shapiro-Wilk test and bivariate analysis within the group exposed to ARDS and the one not exposed, as well as Fisher's, Wilks G, chi-square tests, and Poisson logistic regression were applied, with significant variables p <0.05 and 95% CI. From que 181 pediatric cancer patients included in the study, 69.06% had ARDS, with 48% leukemia, 58.4% pneumonia, 60.8% febrile neutropenia, and 76.1% were in the maintenance chemotherapy phase; pH expressed higher relation with ARDS outcome and mortality. These data are important as this is one of the first studies carried out on ARDS in the pediatric cancer population in the North of Brazil, but further research is needed to better correlate risk factors and acute respiratory distress syndrome on such population.

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Section: Discussionsupporting

confidence: 91%

Risk factors in acute respiratory distress syndrome among children with cancer in Brazilian Amazon: An observational study

Farias¹,

Júnior²,

Dias³

et al. 2021

RSD

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“…In relation to the stage of chemotherapy treatment, 20.8% of the population were in the maintenance stage. The treatment is divided into stages, and the maintenance stage is the most extensive (22) . Therefore, the high incidence of children and adolescents in this stage in this study is due to the fact that it corresponds to the longest period of treatment.…”

Section: Discussionmentioning

confidence: 99%

Impaired comfort in children and adolescents with cancer

et al. 2018

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Pulmonary function of children with acute leukemia in maintenance phase of chemotherapy

Abstract: Children with acute leukemia, myeloid or lymphoid, during the maintenance phase of chemotherapy exhibited unchanged spirometric variables and maximal expiratory pressure; However, there was a decrease in inspiratory muscle strength.

Cited by 2 publications

References 18 publications

Risk factors in acute respiratory distress syndrome among children with cancer in Brazilian Amazon: An observational study

Risk factors in acute respiratory distress syndrome among children with cancer in Brazilian Amazon: An observational study

Impaired comfort in children and adolescents with cancer

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