An evaluation of the protective effect of an infusion of chilled glucose solution on thermal injury of the bile ducts caused by radiofrequency ablation of the liver

Talasso, Marcelo Salim; Lanzoni, Valéria Pereira; Goldenberg, Alberto; Garcia, Rodrigo Gobbo; Moura-Franco, Rita Maria Aparecida; Fernandes, Olivia; Mesquita, Rafael de Souza; Carlotto, Jorge Roberto Marcante; Matos, Délcio; Filho, Gaspar de Jesus Lopes; Linhares, Marcelo Moura

doi:10.1590/s0102-86502015001000005

Cited by 4 publications

(1 citation statement)

References 22 publications

(21 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, in our previous in vivo experiment conducted on rabbits, the cooling effect was very localized and did not spread beyond the arteries. 18 We did not use any chilling techniques aimed at maintaining a constant temperature in the bile ducts 42 and thus allowing simulation of uninterrupted bile flow. We do not know what effect the chilling approach might have had on the local thermal spread in our case, but given the slow rate of bile flow, we hypothesize that it would have been insignificant.…”

Section: Discussionmentioning

confidence: 99%

Thermal Processes in Bile Ducts During Laparoscopic Cholecystectomy with Monopolar Instruments. Experimental Study Using Real-Time Intraluminal and Surface Thermography

et al. 2020

View full text Add to dashboard Cite

Introduction. A significant rate of complications during laparoscopic cholecystectomy (LC) occurs due to thermal injury caused by monopolar electrosurgery (MES) equipment. Most of them manifest weeks and months after surgery with the common bile duct (CBD) and large duodenal papilla strictures, some in the early postoperative period with bile leaks. Objective. To study thermal processes occurring in the lumen and on the surface of the bile ducts during monopolar coagulation in a porcine model of LC. Methods. The temperature of the bile ducts was measured using instrumentation consisted of biliary stent with temperature sensors, which was inserted in the porcine CBD, signal amplifier, and current sense transformer. Surface temperature was measured with a scientific grade thermal camera. Cholecystectomy was performed using a standard “critical view of safety” (CVS) approach with 5 mm monopolar laparoscopic instruments. Results. Application of MES caused significant tissue heating. Lateral thermal spread and the rate of tissue heating depended on the duration of energy application and the initial tissue temperature. In 5 out of 6 experiments, the intraluminal temperature rose up to the critical threshold, and the exposure time ranged from 54 to 560 seconds. A sensor positioned at the papilla site was heated in all the experiments but still below the cell damage inducing threshold. The analysis of thermographic charts revealed the presence of the “current channeling” effect and the pedicle effect. Conclusion. There is a possibility of a direct and delayed thermal injury to the bile ducts during LC.

show abstract

Section: Discussionmentioning

confidence: 99%

Thermal Processes in Bile Ducts During Laparoscopic Cholecystectomy with Monopolar Instruments. Experimental Study Using Real-Time Intraluminal and Surface Thermography

et al. 2020

View full text Add to dashboard Cite

show abstract

A case of hepatocellular carcinoma treated by radiofrequency ablation confirming the adjacent major bile duct under hybrid contrast mode through a biliary drainage catheter

Imai

Hirooka

Ochi

et al. 2015

Clin J Gastroenterol

View full text Add to dashboard Cite

Bile duct injury is a potential complication of radiofrequency ablation (RFA). Bipolar RFA devices have recently become available. Because visibility of the bipolar RFA electrodes is not good on ultrasonography, more careful usage of the electrodes to avoid bile ducts is needed. We present a case with hepatocellular carcinoma (HCC) located near the B5 intrahepatic bile duct. To view the bile duct, we used contrast medium for ultrasonography, administered through a biliary drainage catheter for endoscopic nasobiliary drainage (ENBD). Infusing the contrast medium allowed clear visualization of the HCC adjacent to the major bile duct during RFA. We also used a navigation system for bipolar RFA to confirm positions of the electrodes and HCC. We confirmed complete ablation of the HCC while avoiding bile duct injury and late bile duct stenosis. Administration of contrast medium for ultrasonography through an ENBD tube appears useful to avoid bile duct injury during RFA.

show abstract

Thermal ablation for hepatic tumors in high-risk locations

Ndhlovu,

Zhang,

Chen

et al. 2024

Clinics and Research in Hepatology and Gastroenterology

View full text Add to dashboard Cite

An evaluation of the protective effect of an infusion of chilled glucose solution on thermal injury of the bile ducts caused by radiofrequency ablation of the liver

Abstract: Infusion of 5% glucose solution (5°C) has a protective effect on bile ducts subjected to heat (95-110°C, 12 min) from radiofrequency thermal ablation device.

Cited by 4 publications

References 22 publications

Thermal Processes in Bile Ducts During Laparoscopic Cholecystectomy with Monopolar Instruments. Experimental Study Using Real-Time Intraluminal and Surface Thermography

Thermal Processes in Bile Ducts During Laparoscopic Cholecystectomy with Monopolar Instruments. Experimental Study Using Real-Time Intraluminal and Surface Thermography

A case of hepatocellular carcinoma treated by radiofrequency ablation confirming the adjacent major bile duct under hybrid contrast mode through a biliary drainage catheter

Thermal ablation for hepatic tumors in high-risk locations

Contact Info

Product

Resources

About