The use of the external layer of the calvaria's frontal bone to repair craniofacial skeleton injuries in Macaca mulatta (Rhesus)

Abstract

PURPOSE: To study the integration of the external layer of the calvaria's frontal bone to repair craniofacial skeleton injuries in primates. METHODS: Ten Rhesus monkeys underwent surgery in two stages. In the first stage, four bone fragments were harvested from the external layer of the calvaria's frontal bone and were transplanted two on the calvaria's frontal bone and the other two onto the maxillary bone, by onlay and inlay. Seven weeks thereafter, four fragments were extracted from the transplantated area. The animals were not sacrificed. RESULTS: Macroscopic examination reveals bone regeneration, the areas onto which the bone fragments were transplantated having consequently increased in volume. The results of optical and electron microscopy is being carried out.