Importância da preservação de tecido esplênico para a fagocitose bacteriana

Marques, Ruy Garcia; Petroianu, Andy; Oliveira, Mariana Borges; Filho, Mário Bernardo

doi:10.1590/s0102-86502002000600006

Cited by 8 publications

(9 citation statements)

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“…Mediu-se também o colóide remanescente no sangue, com o objetivo de verificar a eficácia da função depuradora do SMF. A presença de valores muito reduzidos de colóide radioativo na circulação indicou que o SMF das ratas de todos os grupos desempenhou adequadamente o seu papel de remover partículas anômalas da circulação (28) . Para a marcação de diferentes estruturas biológicas, vários radiofármacos vêm sendo utilizados, como carbono, gálio, hidrogênio, rênio, tecnécio, entre outros (8,17,21) .…”

Section: Discussionunclassified

Influência da ooforectomia e da gravidez na função fagocitária do sistema mononuclear fagocitário em modelo experimental

Vasconcellos

Sabino

Petroianu

2005

J. Bras. Patol. Med. Lab.

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Section: Discussionunclassified

Influência da ooforectomia e da gravidez na função fagocitária do sistema mononuclear fagocitário em modelo experimental

Vasconcellos

Sabino

Petroianu

2005

J. Bras. Patol. Med. Lab.

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“…In order to reduce these complications, total splenectomy has been progressively replaced by procedures that preserve the splenic tissue 2 . The better knowledge of the spleen and its functions has influenced the use of less invasive procedures 3,4 .…”

Section: Introductionmentioning

confidence: 99%

Phagocytic function of lower spleen pole and autogenous splenic implants in rats

et al. 2014

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PURPOSE:To investigate whether there are differences between the phagocytic function of the remaining lower spleen pole after subtotal splenectomy and autogenous splenic implants. METHODS:Thirty-six male Wistar rats, weighting 364 ± 60g were used. They were subjected to subtotal splenectomy preserving the lower spleen pole and to autogenous splenic implant in the greater omentum. Its viability was assessed microscopically. Phagocytic function was assessed by splenic uptake of the radioisotope-labeled colloid and by macrophages counting. RESULTS:The viability of the autogenous splenic implant and of the lower spleen pole was found in 33 animals, with no difference between them. The weight of the implants was higher than the lower pole of animals from groups G1, G7, G30, G60 and G120. The implants phagocytic function by radioisotope uptake was higher than the lower pole in G7 and G120 groups and it did not differ from the other groups. The number of macrophages was higher in G1, G60, G90 and G120 and did not differ from the other groups. CONCLUSION:Until the 16th week, the phagocytic function was more pronounced in autogenous splenic implants when compared with the lower spleen pole, but it became similar thereafter.

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“…In this situation, the laparoscopy is converted into a laparotomy, culminating with a splenectomy due to the hemorrhage caused by the puncture. A l t h o u g h the spleen is not necessary for survival, this lymphoid organ has important immune functions, such as bacterial clearance of the bloodstream and antibody production (MARQUES et al, 2002). Moreover, the spleen is responsible for filtrating large blood volumes; this process removes senescent and altered erythrocytes and corpuscular inclusion (MARQUES et al, 2002).…”

Section: Introductionmentioning

confidence: 99%

“…A l t h o u g h the spleen is not necessary for survival, this lymphoid organ has important immune functions, such as bacterial clearance of the bloodstream and antibody production (MARQUES et al, 2002). Moreover, the spleen is responsible for filtrating large blood volumes; this process removes senescent and altered erythrocytes and corpuscular inclusion (MARQUES et al, 2002). Teixeira et al (2008) reported that splenectomy results in a high rate of sepsis.…”

Section: Introductionmentioning

confidence: 99%

Congestão esplênica associada a aplicação de acepromazina em cães

Tavares

Souza

Olivaes

et al. 2014

Braz. J. Vet. Res. Anim. Sci.

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The effects splenic dilatation induced by acepromazine in a prospective, randomized study. Thirtythree adult mongrel dogs were divided into two groups designated as AG (acepromazine 0.05 mg/kg, i.v., n = 23) and CG (0.9% sodium chloride administered at a similar volume, n = 10). In both groups underwent sonographic examinations before (T0) and fifteen minutes (T15) after drug injection. The thickness spleen and splenic vein width were measured. Higher thickness was found in the AG group at T15 (2.47 cm) when compared to that at T0 (2.06 cm, p = 0.016), while the T0 (2.33 cm) and T15 (2.39 cm) measures did not differ within the CG group. Moreover, the splenic vein width was higher (p = 0.013) at T15 than at T0 in the AG group. Based on results of this study, we concluded that acepromazine, in doses of 0.05 mg/kg, promotes splenomegaly in dogs after fifteen minutes of the injection.Keywords: Canis lupus familiaris. Phenothiazines. Splenomegaly. ResumoForam avaliados os efeitos de dilatação esplênica induzidos pela acepromazina em estudo do tipo prospectivo e randomizado. Trinta e três cães foram distribuídos em dois grupos designados como GA (acepromazina 0,05 mg/kg, i.v., n = 23) e GC (solução de cloreto de sódio 0,9% em volume semelhante ao GA, i.v., n = 10). Em ambos os grupos foi realizada ultrassonografia abdominal previamente à aplicação das substâncias (T0) e após 15 minutos (T15). A espessura do baço e a largura da veia esplênica foram mensuradas. Foi verificada maior espessura esplênica no GA no T15 (2,47 cm) quando comparado a T0 (2,06 cm, p = 0,016), enquanto no GC não houve diferença significativa, sendo T0 (2,33 cm) e T15 (2,39 cm). Ainda, a largura da veia esplênica foi maior no T15 (p = 0,013) comparado a T0 no GA. Baseado nos resultados encontrados, pode-se concluir que a acepromazina na dose de 0,05 mg/kg induz a esplenomegalia em cães após 15 minutos da aplicação. Palavras-chave:Canis lupus familiaris. Fenotiazínicos. Esplenomegalia.

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Importância da preservação de tecido esplênico para a fagocitose bacteriana

Cited by 8 publications

References 10 publications

Influência da ooforectomia e da gravidez na função fagocitária do sistema mononuclear fagocitário em modelo experimental

Influência da ooforectomia e da gravidez na função fagocitária do sistema mononuclear fagocitário em modelo experimental

Phagocytic function of lower spleen pole and autogenous splenic implants in rats

Congestão esplênica associada a aplicação de acepromazina em cães

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