Vaporizador artesanal de éter para cirurgia experimental em pequenos roedores

Abstract

O presente trabalho descreve modelo experimental de vaporizador artesanal de éter, modificado a partir do modelo de WAYNFORTH &amp; FLECKNELL, a fim de manter fluxo contínuo e homogêneo do anestésico em cirurgias onde se utiliza roedores de pequeno porte como animais de experimentação. O sistema é construído a partir de material encontrado em casas de materiais para aquários, sonda e tubo de ensaio de uso hospitalar, base de madeira e campânula de vidro confeccionada em vidraçaria. Como vantagens do sistema pode-se citar a manutenção do animal em plano anestésico sem que haja necessidade de contínuas "induções" com algodão embebido em éter e ofertado por via nasal, com perda do excesso para o meio ambiente e inalação do mesmo por quem conduz o experimento. Diminui-se assim quantidade de anestésico total gasto, devido manter-se níveis de oferta mais homogêneas por um fluxo contínuo de acordo com o plano anestésico do animal. Consegue-se também através do consumo aferido no tubo de ensaio, calcular aproximadamente o volume / minuto inalado, consumindo-se em média 5 ml de éter em uma hora de anestesia para ratos com 300g, obtendo com isto economia da substância, melhor controle da quantidade inalada pelo animal e redução da poluição do meio ambiente pelo mesmo.<br>This paper described a homemade ether vaporizer, changed from WAYNFORTH &amp; FLECKNELL model for small animals. The device is build with hospital material and products bought in aquarium’s shops. Their advantages are maintenance of anesthetic level without successive "inductions" by inhalatory nasal ether ; ether consumption of 5 ml per hour in animals with 300 g ; smaller ambient pollution and small cost. The disadvantages are a hardness and reduction of the plastic tubes after approximately 150 hour in use, by ether action and the necessity of experience acquisition in anesthetic manipulation with the devic

Proliferative effect of aqueous extract of Hyptis fructicosa on liver regeneration after partial hepatectomy in rats

“…In order to improve anesthesia performance and prevent problems such as air pollution, unstable anesthesia level and anesthetic wastefulness, an ether vapourizator for little rodents was used 9,10 . The median and left lateral lobes of the liver (corresponding to 67% of the organ) were excised 11 .…”

Inhalation anesthesia equipment for rats with provision of simultaneous anesthetic and oxygen

“…The authors of the present study demonstrate modifications to the equipment that is described by Brito et al 2,4 , with the additional advantages of oxygen availability and better control of the flow of the anesthetic agent with minimal loss to room air, making the equipment more useful and practical.…”

“…Notwithstanding the great improvements made by Brito et al 2,4 in anesthetic equipment models for rats, the construction of this anesthetic equipment came from a need to resolve persistent problems with inhalation anesthesia 5 . This new method retains such advantages of Brito´s model 2,4 as low cost, ease of use, acceptable level of tracheobronchial secretions during induction, a small amount of anesthetic agent used and lost to the environment 5 .…”

“…For these procedures, inhalation anesthesia is typically induced by a cotton-wool ball soaked in an inhalation agent (generally ethyl ether) that is placed within a closed chamber or box 1,2 . This same cotton ball is held near the animal´s muzzle in order to maintain anesthesia during surgery 3 .…”

“…This method has several disadvantages: the anesthetic escapes into the room air, respiratory depression often occurs due to difficulties controlling the volume of ether, induction is prolonged, and maintenance of a consistent anesthetic level is difficult because when the cotton ball is held against the animal´s muzzle, upper airway resistance increases 1 . Brito et al 2,4 successfully developed equipment to reduce the impact of these issues.…”