Operação de Ross com homoenxertos valvares decelularizados: resultados de médio prazo

Costa, Francisco da; Dohmen, Pascal M.; Vieira, Eduardo; Lopes, Sergio Veiga; Colatusso, Claudinei; Pereira, Elaine Welk Lopes; Matsuda, Camila Naomi; S, Cauduro

doi:10.1590/s0102-76382007000400012

Cited by 34 publications

(21 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Decellularization of heterografts by the deoxycholic acid (DOA) shows good experimental [13] and clinical outcomes at a 24-month observation period [14]. A number of decellularization methods shows to be promising, such as the sodium dodecyl sulfate (SDS), which is used in homografts [15] as many other surface-active agents [16]. The outstanding method in clinical practice today, the cryopreservation, with proven results, although it is not the ideal, because it comes up against the complexity, high cost, difficulty of transport to remote regions, poor sterilization of some organisms, and degeneration in the long term, especially in young people [17,18].…”

Section: Discussionmentioning

confidence: 99%

Estudo experimental comparativo do enxerto homólogo pulmonar tratado pelo processo L-Hydro com o homoenxerto pulmonar a fresco

Rey

Moreira

Cheung

et al. 2011

Rev Bras Cir Cardiovasc

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Estudo experimental comparativo do enxerto homólogo pulmonar tratado pelo processo L-Hydro com o homoenxerto pulmonar a fresco

Rey

Moreira

Cheung

et al. 2011

Rev Bras Cir Cardiovasc

View full text Add to dashboard Cite

“…In the last years, the cardiac surgery service of Santa Casa de Curitiba chose to use the pulmonary homograft for reconstructing the right ventricle exit tract due to its technical advantages and the good clinical and surgical results of the already operated patients 2,3 . The option of this service for the use of the pulmonary homograft, in such position, is based on studies that show that the aortic homograft in pulmonary position presents higher index of calcification due to its composition rich in elastin [4][5][6][7][8][9][10][11][12][13][14][15] .…”

Section: Discussionmentioning

confidence: 99%

Disfunção do homoenxerto pulmonar utilizado na reconstrução do trato de saída do ventrículo direito

Lenzi¹,

Olandoski²,

Ferreira³

et al. 2011

Arq. Bras. Cardiol.

View full text Add to dashboard Cite

show abstract

“…They present good midterm outcomes, with decreased pulmonary failure, prolonging the graft's life [4].…”

Section: Introductionmentioning

confidence: 98%

Mortalidade hospitalar na cirurgia de reconstrução da via de saída do ventrículo direito com homeonxerto pulmonar

Lenzi

Miyague²,

Ferreira

et al. 2010

Rev Bras Cir Cardiovasc

View full text Add to dashboard Cite

Mortalidade hospitalar na cirurgia de reconstrução da via de saída do ventrículo direito com homeonxerto pulmonarHospital mortality in surgery for right ventricular outflow tract reconstruction using pulmonary homograft Abstract Background: Hospital mortality in surgical reconstruction of the right ventricular outflow tract using pulmonary homograft is variable.Objectives: To identify risk factors associated with hospital mortality and patients' clinical profile.Methods: Study on children who had undergone reconstruction of the right ventricular outflow tract using pulmonary homograft. We analyzed as risk factors the clinical and surgical variables and prosthesis's morphological aspects.Results: Ninety-two patients underwent surgery between 1998 and 2005, presenting mainly pulmonary atresia with ventricular septal defect and tetralogy of Fallot. Forty patients were treated in the first month of life. 38 patients needed Blalock Taussig surgeries due to clinical severity. The median age at surgery for total correction was 22 months, ranging from 1 to 157 months. Pulmonary homograft size ranged from 12 to 26 mm and length of cardiopulmonary bypass was 132 ± 37 minutes. Postoperatively, there were seventeen deaths (18% cases), on average 10.5 ± 7.5 days after surgery. The predominant cause was multiple organ failure. In the univariate analysis between the types of heart disease, they related to age, time of surgery, size of homograft, pulmonary valve Z value, CPB time, maintenance of the integrity of the homograft and pulmonary tree change. There was no statistical difference in hospital mortality between the variables and the type of heart disease.Conclusion: The right-sided obstructive heart diseases require surgical care in the first days of life. The total correction surgery has a mortality risk rate of 18% but there was no association with any variable studied.Descriptors: Heart defects, congenital. Cardiovascular surgical procedures. Transplantation, homologous. Mortality. Resumo

show abstract

Operação de Ross com homoenxertos valvares decelularizados: resultados de médio prazo

Abstract: The use of decellularized allografts was safe and with good medium-term results up to 4 years. There was a tendency to lower late gradients in the SDS decellularized allografts after 12 months.

Cited by 34 publications

References 18 publications

Estudo experimental comparativo do enxerto homólogo pulmonar tratado pelo processo L-Hydro com o homoenxerto pulmonar a fresco

Estudo experimental comparativo do enxerto homólogo pulmonar tratado pelo processo L-Hydro com o homoenxerto pulmonar a fresco

Disfunção do homoenxerto pulmonar utilizado na reconstrução do trato de saída do ventrículo direito

Mortalidade hospitalar na cirurgia de reconstrução da via de saída do ventrículo direito com homeonxerto pulmonar

Contact Info

Product

Resources

About