Bicaval/bipulmonary orthotopic heart transplantation

Dinkhuysen, Jarbas J

doi:10.1590/s0102-76382003000300012

Cited by 3 publications

(1 citation statement)

References 4 publications

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“…The bicaval/bipulmonary technique was the procedure used for HT in our institution . All patients were treated with 10 mg/kg of methylprednisolone and prophylactic antibiotic therapy as part of the standard pre‐operative evaluation.…”

Section: Methodsmentioning

confidence: 99%

Donor hypernatremia and smoking addiction contribute to primary graft failure in heart transplantation

Finger

Cipullo

Neto

et al. 2019

Clinical Transplantation

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Introduction: Primary graft failure (PGF) is an important contributor to early mortality, accounting for 41% of deaths within the first 30 days after heart transplantation (HT). Donor hypernatremia has been associated with PGF development. However, controversial data exist regarding the impact of sodium deregulation in patient survival after HT. This study aimed to assess the influence of donor hypernatremia on PGF development and to determine the serum sodium level threshold to assist in decision-making for organ procurement. Methods:The medical record from 200 HT patients and organ donors were retrospectively assessed and categorized by PGF occurrence. Donor sodium levels were compared and cut-off points obtained by receiver operating characteristic (ROC) curve. A multiple logistic regression model was applied to assess the effects of factors and covariates that influence PGF development.Results: Sodium levels of donors were significantly higher in recipients who developed PGF than those who did not develop PGF (162 vs. 153 mmol/L, P = .001). The sodium cut-off value determined by the ROC curve was 159 mmol/L. The group who received organs from donors with a serum sodium concentration ≥159 mmol/L had a higher incidence of PGF (63.3% vs 32.4%, P < .001). Furthermore, donor sodium levels ≥159 mmol/L increased the likelihood of recipients developing PGF by 3.4 times. It is also observed that the incidence of donor smoking addiction was significantly higher in the PGF group (28.6% vs. 11.5%, P = .004) and donor smoking addiction increased the risk of developing PGF by 2.8 times. Conclusion:Smoking addiction and the application of suboptimal organs from donors with hypernatremia contribute to primary graft failure in heart transplantation. K E Y W O R D Sgraft survival, heart transplantation, hypernatremia, organ donors, primary graft dysfunction

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Section: Methodsmentioning

confidence: 99%

Donor hypernatremia and smoking addiction contribute to primary graft failure in heart transplantation

Finger

Cipullo

Neto

et al. 2019

Clinical Transplantation

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Variáveis perioperatórias de função ventilatória e capacidade física em indivíduos submetidos a transplante cardíaco

Coronel

Bordignon²,

Bueno³

et al. 2010

Rev Bras Cir Cardiovasc

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Introduction: Heart transplantation is currently the only widely accepted surgical alternative to treat patients with severe heart failure (HF) drug therapy cannot maintain optimal quality of life appropriate.Objective: To describe and to compare the values between pre-and postoperative physical capacity and pulmonary patients who underwent heart transplantation.Methods: A retrospective cohort composed of patients undergoing heart transplantation between January 2001 to March 2005 in IC-FUC/RS.Results: Were included in the 21 individuals. We observed decreased levels of volume and lung capacity (FEV1 and FVC) in the first days after surgery compared to preoperatively (P <0.001) and recovery of these values in the 14th postoperative day (P <0.001). The values of muscle strength showed similar trends in reducing post-operative period compared to preoperative (P <0.001) and recovered on the 14 th postoperative day (P <0.001). A useful functional capacity, measured by testing 6-minute walk test (T6') showed improvement in the 14 th postoperative day in relation to pre-operatively (P <0.001). Conclusion:Changes in ventilatory function of subjects undergoing cardiac transplantation are predictable, but these recover respiratory muscle strength and lung capacity within two weeks, and improve functional capacity useful in relation to pre-operative, the transplantation, when indicated, associated with good functional rehabilitation is very god treatment strategy.Descriptors: Heart transplantation. Respiratory function tests. Forced expiratory flow rates. Exercise therapy. ResumoIntrodução: O transplante cardíaco é atualmente a única alternativa cirúrgica amplamente aceita para tratar pacientes com insuficiência cardíaca (IC) grave que a terapia medicamentosa otimizada não consiga manter qualidade de vida adequada.Objetivo: Descrever e comparar os valores entre pré e pós-operatório, das capacidades física e pulmonar de pacientes que realizaram transplante cardíaco. Bras Cir Cardiovasc 2010; 25(2): 190-196 bed, coughing and control techniques of pain [7,12], in addition to the practice of aerobic exercises. [17]. CORONEL, CC ET AL -Perioperative variables of ventilatory function and physical capacity in heart transplant patients RevDespite all the risks that patients with transplanted organ has to infection and rejection, this technique has shown great efficacy in survival, presenting results of survival rate of 90% in the first year and 87% in the fifth year posttransplant with good quality of life [18].This study aims to describe the values of physical and pulmonary abilities of patients who underwent heart transplant and who underwent conventional physiotherapy. Moreover, it aims to evaluate and compare the physical capacity of patients preoperatively and on day 14 th postoperative heart transplant and to evaluate and compare the forced vital capacity, forced expiratory volume in one second, maximum inspiratory muscle strength and the maximal expiratory muscle strength in pre-, 1st, 7th and 14 th postoperativ...

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Teste farmacológico pré-implante na hipertensão pulmonar elevada e fixa em candidatos a transplante heterotópico

Dinkhuysen

Cipullo²,

Contreras³

et al. 2010

Rev Bras Cir Cardiovasc

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Teste farmacológico pré-implante na hipertensão pulmonar elevada e fixa em candidatos a transplante heterotópicoFarmacologic test pre-implants in hypertension pulmonary elevated and still in candidates to heterotopic transplantation This study was carried out at Instituto Dante Pazzanese de Cardiologia/ SP, São Paulo, SP, Brazil. Results: The intraoperative findings were: Pre NP (mmHg) e Post NP (mmHg), respectively, PSAS 91-78 (8.5 ± 5.2) and 65-59 (4.2 ± 63.8) (P = 0.017), decrease 19.9%, decrease 29.3%; PSAP 71-52 (61.8 ± 6.1) and 43-32 (37.5 ± 3.3) (P = 0.018), decrease 28%, decrease 41%. In light of these data, patients were transplanted by orthotopic technique not being observed mortality in the short and long-term evolution from 5 months to 6 years.Conclusion: This methodology allowed the conversion of the technique for heterotopic orthotopically, with good early and late otcomes. Conclusão: A aplicação desta metodologia permitiu a conversão da técnica heterotópica para ortotópica, com bons resultados imediatos e tardios.Descritores: Hipertensão pulmonar. Transplante de coração. Artéria pulmonar.

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Bicaval/bipulmonary orthotopic heart transplantation

Cited by 3 publications

References 4 publications

Donor hypernatremia and smoking addiction contribute to primary graft failure in heart transplantation

Donor hypernatremia and smoking addiction contribute to primary graft failure in heart transplantation

Variáveis perioperatórias de função ventilatória e capacidade física em indivíduos submetidos a transplante cardíaco

Teste farmacológico pré-implante na hipertensão pulmonar elevada e fixa em candidatos a transplante heterotópico

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