Variation in phenolic compounds of Ugni molinae populations and their potential use as antioxidant supplement

Abstract

In the present work we carried out a comparative study of total phenolic contents and antioxidant capacity of aqueous leaf extracts of Ugni molinae Turcz., Myrtaceae (infusion and Soxhlet extracted) prepared from continent and Juan Fernández Island samples. The results revealed that total phenol content (TPC), tannins (TTC) and flavonoids (TFC) for U. molinae extracts (infusion and Soxhlet extracts) from island leaves were 38.5, 56.7 and 37.5% higher than those obtained with leaves from the continent, respectively. Also, HPLC profiles showed important differences between U. molinae populations. In vitro antioxidant capacity (scavenging of DPPH radical) for 1% infusion and aqueous extract (Soxhlet method) of U. molinae from island samples, was 15% greater than from continent samples. Further, in vivo impact of U. molinae intake (1% infusion) was studied in plasma samples obtained from healthy volunteers. Participants that consumed tea prepared with leaves from island population showed higher TBARS reduction and plasma antioxidant capacity (TEAC-CUPRAC) than those who consumed tea prepared with leaves from continental population. The conditions of the territory in which U. molinae populations growth could explain the differences in their composition and activity. According to results, island U. molinae populations could be an important source of study for the development of an antioxidant supplement, and thereby contribute to the use of this species that has becoming an ecological problem in the island

Phenolic profile and antioxidant activity of Capparis spinosa seeds harvested from different wild habitats

“…Results clearly showed that the level of polyphenols varied largely between samples from different regions. These findings agree well with previous reports indicating that secondary metabolite content may vary among locations (Avello et al, 2013;Chetoui et al, 2013;Tlili et al, 2010). Indeed, climatic conditions may influence phenolic compound synthesis as a response to the possible oxidative stress due to the generation of reactive oxygen species in aggressive environments (de Abreu and Mazzafera, 2005;Lamien-Meda et al, 2010).…”

“…However, the differences observed between samples from different locations were similar to many reports for other species such as pomegranate, Ugni molinae, Salvia and Rhus species (Avello et al, 2013;Ben Farhat et al, 2013;Mphahlele et al, 2014;Tlili et al, 2014). It is important to note that numerous peaks remained unidentified; these peaks could provide helpful information to more strongly confirm the medicinal and nutritional importance of C. spinosa.…”

Metabolite profiling, antioxidant and antibacterial activities of Brazilian propolis: Use of correlation and multivariate analyses to identify potential bioactive compounds

“…Taken together, these results support the fact that GPD and GPE are the fractions with the highest antioxidant capacity (Table 2). Several studies have reported the antioxidant properties of the phenolic compounds (Avello, Pastene, Bustos, Bittner, & Becerra, 2013;Pereira et al, 2014;Wang et al, 2013). A recent study has evaluated the antioxidant capacity of free retinoic acid by four different scavenging assays.…”

In vivo antioxidant activity of phenolic compounds: Facts and gaps

“…Phenolic compounds have shown promising antioxidant properties, with its potential being directly related with the type of solvent used in the extraction, but also with plant origin, growing conditions, harvesting time, and storage conditions (Avello, Pastene, Bustos, Bittner, & Becerra, 2013;Taârit, Msaada, Hosni, & Marzouk, 2012;Trabelsi et al, 2012). The study of the antioxidant potential of phenolic extracts derived from plant species is one of the hot topics among the scientific community; however, in vitro studies are the most common (Dai & Mumper, 2010;Larrosa, García-Conesa, Espín, & Tomás-Barberán, 2010;Rubió, Motilva, & Romero, 2013).…”