Metabolite profiling, antioxidant and antibacterial activities of Brazilian propolis: Use of correlation and multivariate analyses to identify potential bioactive compounds

Bittencourt, Mara L.F.; Ribeiro, Paulo R.; Franco, Rosana L.P.; Hilhorst, Henk W. M.; Castro, Renato Delmondez de; Fernandez, Luzimar Gonzaga

doi:10.1016/j.foodres.2015.07.008

Cited by 118 publications

(94 citation statements)

References 49 publications

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“…Antioxidant potency is usually associated with the content of phenolic compounds due to their extensive conjugated π-electron systems that facilitate the donation of electrons from the hydroxyl moieties to oxidizingradical species. 22 From the calculation data, it is known that PEE from this research are strong antioxidant, according to Jun et al (2003), 25 that classification of antioxidant power are strong antioxidant with strength level (IC 50 <50 ppm), active (IC 50 50-100 ppm), moderate (IC 50 101-250 ppm), weak (IC 50 250-500 ppm), and inactive (IC 50 > 500 ppm). 25 The EC 50 DPPH radical scavenging activity of Propolis in this research are inferior to Bolivian Propolis those reported by Nélida Nina (2016) 17 22 ranged from 21.50 to 78.77 μg/mL.…”

Section: Discussionmentioning

confidence: 79%

Phytochemical Profile and Antioxidant Activity of Propolis Ethanolic Extract from Tetragonula Bee

Pratami¹,

Mun’im²,

Sundowo³

et al. 2017

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Bees produce propolis, a mixture of bee saliva and gum produced by leaf buds and stems, which come out through plant's skin collected by bees. 1 The physical properties of raw propolis are hard and wax-like when fresh, but soft and very sticky when warm. It has a characteristic aromatic smell and odor; its range color varies from light to dark brown, red, yellow, or green, depending on its age and source.2 Chemical composition, which bees collect from the resinous plant parts, may influence its biological effect. 3 The composition of propolis depends on diverse vegetation, phytogeographic region, and time of the collection. 4 Results from previous researchers found more than 300 components contained in propolis i.e. aromatic acids; aromatics esters; flavanones; flavones and flavonol; chalcones and dihydrochalcones; terpenoids; acyclic hydrocarbons and esters; alcohols; aliphatic acids (short-chain); aliphatic esters; aliphatic fatty acids (long-chain) and esters; amino acids; aromatic hydrocarbons; acetophenones and other ketones; glycerol derivatives; steroids; sugars and sugar alcohols; and miscellaneous ingredients. The quantification of the phytochemical content of propolis can be determined Phytochemical Profile and Antioxidant Activity of Propolis Ethanolic Extract from Tetragonula Bee ABSTRACTObjective: This research aimed to determine the phytochemical composition and the antioxidant properties in vitro of three types propolis collected from the region of South Sulawesi Province of Indonesia. Methods: Samples from three types of propolis: smooth, rough and mix were extracted with 96% ethanol. The propolis ethanolic extracts (PEE) was dried and studied their antioxidant properties by using FRAP (Ferric Reducing Antioxidant Power) and DPPH radical scavenging assays. Total phenolic compounds were quantified by Folin-Ciocalteu, and total flavonoid contents were also quantitatively determined by the AlCl 3 colorimetric method with a microplate reader. The chemical compounds were identified by an ultraperformance liquid chromatography TOF mass spectrometer (UPLC-TOF-MS) using the MS E mode.

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Section: Discussionmentioning

confidence: 79%

Phytochemical Profile and Antioxidant Activity of Propolis Ethanolic Extract from Tetragonula Bee

Pratami¹,

Mun’im²,

Sundowo³

et al. 2017

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“…) (Table S2). Based on these results we can conclude that the mechanisms underlying the antimicrobial as well as the antioxidant activities involved composite features reflected by synergistic or antagonistic effects among the metabolites existing within the extracted oils or extracts (Sasidharan et al ., ; Bittencourt et al ., ; Pérez et al ., ).…”

Section: Resultsmentioning

confidence: 99%

Correlative metabolite profiling approach to understand antioxidant and antimicrobial activities from citrus essential oils

Lamine

Rahali

Hammami

et al. 2019

Int J of Food Sci Tech

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The objective of this study was to investigate the chemical composition of the essential oils from citrus species, as well as their antioxidant and antimicrobial activities. By gas chromatography-mass spectrometry, we identified thirty-seven metabolites and a range of unique compounds, contributing to the discrimination of the species. Different biological potentialities were detected depending on the species supported the significant effect of the genetic factor. C. aurantium and C. limon exhibited the highest antioxidant activities which make them a potential source of natural preservative. C. limon exhibited the highest antibacterial activities and C. reticulata the highest antifungal activities. Essential oils extracted from these agro-wastes could serve as natural food preservatives to prevent food pathogens and then extending the shelf life. A set of potential metabolites could be implicated in the observed biological activity, underlying that the antimicrobial activity is a complex trait.

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“…It should be stressed that red propolis has been suggested to be the only propolis type derived from a plant from the Leguminosae family (D. ecastaphyllum), rich in isoflavones such as genistein and formononetin. Although flavonoids exhibit pleiotropic activity affecting several different targets, and synergistic effects cannot be ruled out, our results suggest that the isoflavone formononetin is responsible at least partially for the antimicrobial activity of red propolis 20 Bittencourt et al [30] Twenty-nine metabolites were identified along with 34 other metabolites that were classified into the following classes: triterpenoids (12), acetyltriterpenoids (3), sesquiterpenes (6), steroids (4), and hydrocarbons (9). The antioxidant capacity (IC50) ranged from 21.50 to 78.77 μg/mL, whereas the content of total phenolic compounds ranged from 31.88 to 204.30 mg GAE/g of dry weight.…”

Section: N°bibliographic Referencementioning

confidence: 77%

Beekeeping in Brazil: A Bibliographic Review

Araújo¹,

Araújo²,

Viana³

et al. 2020

Beekeeping - New Challenges

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Brazil presents favorable conditions for beekeeping, having a suitable climate; native flowering plants with great potential for the production of honey, pollen, propolis, and royal jelly; and bees adapted to our conditions, tolerant to the main apicultural diseases and highly productive. Through the meliponiculture, the conservation of mainly native forest areas is allowed; therefore, they are the best environments for the creation of native bees and production of by-products of the beehive with quality. The stingless bees are very sensitive to any disturbance due to anthropogenic action. A systematic bibliographical review was carried out in different electronic databases, through descriptors referring to beekeeping in Brazil. The identification of articles and their inclusion occurred between January 2018 and April 2018. The bibliographic research was conducted in the following electronic databases: (1) Scientific Electronic Library Online (SciELO), (2) Public Library of Science (PLOS) Biology, and (3) ScienceDirect. In order to help in the process of standardization of bee products and traceability of the production chain, it was possible to draw a profile of the main bioactive substances of the beehive products of Brazil. It was also possible to relate the benefits of an adequate management of beekeeping and meliponiculture in Brazil.

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Metabolite profiling, antioxidant and antibacterial activities of Brazilian propolis: Use of correlation and multivariate analyses to identify potential bioactive compounds

Cited by 118 publications

References 49 publications

Phytochemical Profile and Antioxidant Activity of Propolis Ethanolic Extract from Tetragonula Bee

Phytochemical Profile and Antioxidant Activity of Propolis Ethanolic Extract from Tetragonula Bee

Correlative metabolite profiling approach to understand antioxidant and antimicrobial activities from citrus essential oils

Beekeeping in Brazil: A Bibliographic Review

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