Chemical constituents of Rourea doniana

Abstract

Abstract:The chromatography fractionation of the hexane, chloroform and ethyl acetate extracts from the leaves and stems of Rourea doniana Baker, Connaraceae, resulted in the isolation of five triterpenes (lupeol, lupenone, α-amyrenone, β-amyrenone, and taraxerol), a flavonol (7,4'-dimethylkaempferol), a coumarin (scopoletin) and four phytosteroids (β-sitosterol, stigmasterol, β-sitosteryl-3-O-β-D-glucopyranoside and stigmasteryl-3-O-β-D-glucopyranoside). All compounds are being for the first time in this species and all triterpenes and the flavonol are being described for the first time in the family Connaraceae. These compounds were identified on basis of their IR and NMR ( 1 H, 13 C, DEPT, HSQC, HMBC, and NOESY) spectral data and by comparison with literature data.

A New Pyrrolidone Alkaloid and Other Constituents from Rourea oligophlebia Stems

“…e genus of Rourea is a group of climbing shrubs belonging to the family of Connaraceae which are widely distributed in the Amazon, Pacific region, Africa, and Asia [1]. Chemical investigations have revealed that Rourea species contain a substantial number of biologically active constituents, including flavonoids, phytosteroids, triterpenes, lipids, phenolic acids, and coumarins [1][2][3][4][5][6]. e Rourea plant extracts and their active components exhibited interesting biological activities such as hypoglycemic activity [1,5,7], antibacterial activity [1,8], antinociceptive activity [9], antiplasmodial activity [3,10], and antioxidant activity [1,4,8].…”

Highly Cytotoxic Xanthones from Cratoxylum cochinchinense Collected in Myanmar

“…Extensive preparative chromatographic separation of the extract on silica gel and reversed phase columns, under normal as well as medium pressure conditions, afforded the xanthones pruniflorone N (1) [4], pruniflorone M (2) [4], 6-deoxyisojacareubin (3) [5], xanthone V 1 (4) [6], macluraxanthone (5) [3d, 6], 1,5-dihydroxy-8methoxyxanthone (6) [7], 1,7-dihydroxy xanthone (7) [7], 5'demethoxycadesin G (8) [3q], and the anthraquinone vismiaquinone D (9) [8]. In addition, four common triterpenoids, α-amyrin [9], α-amyrenone [10], lupeol [11], and lupenone [12] were isolated.…”