Bioactivity of the compounds isolated from Blepharocalyx salicifolius

Abstract

Blepharocalyx salicifolius (Kunth) O. Berg, Myrtaceae, is an endemic species that occurs at Southern America. This species was studied to intend to isolation of the active compounds that could be used in vitro model against leishmaniosis, tumoral cell and paracoccidioidomycosis. After Gel Permeation Chromatography, the ethanolic extract from leaves yielded sixteen fractions. Five compounds were isolated and assayed, showing activity against tumoral cells, from 3.33 to 12.83 μg.mL -1 ; Leishmania (Leishmania) amazonensis from 2.19 to 20.80 μg.mL -1 and Paracoccidioides brasiliensis from 3.10 to 12.5 μg.mL -1 .

Antioxidant activity and phenol content of extracts of bark, stems, and young and mature leaves from Blepharocalyx salicifolius (Kunth) O. Berg

“…However, few polyphenols were isolated from this species. In the study by Siqueira et al (2011), flavonoids such as quercitrin were isolated from leaf extracts of B. salicifolius, which may be related to antioxidant activity observed in the present study. As seen in Table 1, extracts of bark and stems showed high levels of phenolic compounds and antioxidant activity.…”

“…Infusions of B. salicifolius leaves are used for therapeutic purposes (Ceron et al, 2007) in the treatment of diseases such as sinusitis, cystitis, urethritis, cough, bronchitis, high blood pressure, and rheumatism (Suyenaga et al, 2007;Romero et al, 2012;Piriz et al, 2013;Fuão, 2014). Extracts of plants of this species, are also recognized to have antibacterial, leishmanicidal, anti-inflammatory, and phytotoxic properties (Ceron et al, 2007;Siqueira et al, 2011;Vivot et al, 2012;Habermann et al, 2015b).…”

Phytotoxic potential of young leaves from Blepharocalyx salicifolius (Kunth) O. Berg (Myrtaceae)

“…In work performed by An et al (2000), the ethyl acetate fractions of the leaf extract of Vulpia myuros (Poaceae) were responsible for the highest inhibitory effects on the growth of Triticum aestivum (Poaceae). Flavonoids, such as quercitrin, were identified by Siqueira et al (2011) from the ethanol extract of leaves of Blepharocalyx salicifolius (Myrtaceae). Quercitrin has phytotoxic activity (Iqbal et al, 2002) and may be related to the inhibitory results observed here.…”

“…The leaves of B. salicifolius have know leishimanicidal, antioxidant, antifungal, antimastite, antitumor and anti-inflammatory properties (Ceron et al, 2006;Siqueira et al, 2011;Vivot et al, 2012;Limberger et al, 2001). The phytotoxic potential of the leaf aqueous extracts of this species on bioindicators is also documented in the literature (Alves et al, 2014;Mairesse et al, 2007;Imatomi et al, 2013); however, studies evaluating phytotoxicity of extracts from young leaves in different polarities using organic solvents have not been reported in the literature.…”

Phytotoxic Activity of Stem Bark and Leaves of Blepharocalyx salicifolius (Myrtaceae) on Weeds

“…Nativa da América do sul, encontrase distribuída pelas regiões nordeste, centro-oeste, sudeste e sul do Brasil, sendo ainda encontrada no Uruguai, Paraguai Köeppen (1948), Bolívia e Equador (Lorenzi, 1998). A infusão de suas folhas é utilizada na medicina tradicional como antileucorréico e no tratamento de infecções do trato digestório e urinário (Siqueira et al, 2011;Vivot et al, 2012). Estudos demonstram o potencial fitotóxico dos extratos foliares aquosos de B. salicifolius sobre o desenvolvimento inicial de espécies bioindicadoras como cebola, tomate e alface (Mairesse et al, 2007;Imatomi et al, 2013).…”